ID   RARD_PSEAE              Reviewed;         299 AA.
AC   O68827;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   08-DEC-2000, sequence version 2.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Chloramphenicol-sensitive protein RarD;
GN   Name=rarD; OrderedLocusNames=PA3473;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RA   Xie G., Jensen R.A.;
RL   Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
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DR   EMBL; AF054868; AAC08598.1; -; Genomic_DNA.
DR   EMBL; AE004091; AAG06861.1; -; Genomic_DNA.
DR   PIR; F83211; F83211.
DR   RefSeq; NP_252163.1; NC_002516.2.
DR   RefSeq; WP_003103767.1; NZ_QZGE01000039.1.
DR   AlphaFoldDB; O68827; -.
DR   SMR; O68827; -.
DR   STRING; 287.DR97_4448; -.
DR   TCDB; 2.A.7.7.1; the drug/metabolite transporter (dmt) superfamily.
DR   PaxDb; O68827; -.
DR   EnsemblBacteria; AAG06861; AAG06861; PA3473.
DR   GeneID; 878939; -.
DR   KEGG; pae:PA3473; -.
DR   PATRIC; fig|208964.12.peg.3636; -.
DR   PseudoCAP; PA3473; -.
DR   HOGENOM; CLU_054508_2_0_6; -.
DR   OMA; LMQYIEP; -.
DR   PhylomeDB; O68827; -.
DR   BioCyc; PAER208964:G1FZ6-3541-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   InterPro; IPR004626; RarD.
DR   PANTHER; PTHR22911:SF114; PTHR22911:SF114; 1.
DR   TIGRFAMs; TIGR00688; rarD; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..299
FT                   /note="Chloramphenicol-sensitive protein RarD"
FT                   /id="PRO_0000108155"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        126..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        241..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        58
FT                   /note="W -> L (in Ref. 1; AAC08598)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        126..128
FT                   /note="RLT -> LLM (in Ref. 1; AAC08598)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        138
FT                   /note="A -> S (in Ref. 1; AAC08598)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        293
FT                   /note="K -> T (in Ref. 1; AAC08598)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        296
FT                   /note="R -> Q (in Ref. 1; AAC08598)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   299 AA;  33469 MW;  B9DAAE35F8EAE232 CRC64;
     MRISGQGVLL SLAASVLFVT LPGYVHLLEP LDSLQVVAHR VVWSIPMVFL LVVATRQWPT
     LRAAWCRLFA EPWLLACFPL TAAMMLLQWG IFIWAPLAGK TLELSLGYFL LPLAMVLVGR
     VFYGERLTPL QAIAVACALA GVLHEFWLTR AFSWVSLVTA LGYPPYFMLR RRMGVDALSG
     FVFEMLFLLP LALAALYWLG DESQAFREAP RLWLLLPMLG LISALAFGAM MASSRLLPMG
     LFGILSYVEP VLLFLVAVLF LGEAFRPEQL WTYAPIWLAV LLTGWDSARL LRKQARRGI