RAVL1_ARATH
ID RAVL1_ARATH Reviewed; 361 AA.
AC Q9C6M5;
DT 12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 131.
DE RecName: Full=AP2/ERF and B3 domain-containing transcription repressor TEM1;
DE AltName: Full=Protein TEMPRANILLO 1;
DE AltName: Full=RAV1-like ethylene-responsive transcription factor TEM1;
GN Name=TEM1; OrderedLocusNames=At1g25560; ORFNames=F2J7.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
RN [5]
RP FUNCTION, TISSUE SPECIFICITY, INDUCTION, AND INTERACTION WITH FT.
RX PubMed=18718758; DOI=10.1016/j.cub.2008.07.075;
RA Castillejo C., Pelaz S.;
RT "The balance between CONSTANS and TEMPRANILLO activities determines FT
RT expression to trigger flowering.";
RL Curr. Biol. 18:1338-1343(2008).
RN [6]
RP GENE FAMILY.
RX PubMed=18986826; DOI=10.1016/j.tplants.2008.09.006;
RA Swaminathan K., Peterson K., Jack T.;
RT "The plant B3 superfamily.";
RL Trends Plant Sci. 13:647-655(2008).
CC -!- FUNCTION: Transcriptional repressor of flowering time on long day
CC plants. Acts directly on FT expression by binding 5'-CAACA-3' and 5'-
CC CACCTG-3 sequences. Functionally redundant with TEM2.
CC {ECO:0000269|PubMed:18718758}.
CC -!- SUBUNIT: Interacts with FT. {ECO:0000269|PubMed:18718758}.
CC -!- INTERACTION:
CC Q9C6M5; Q9SQI2: GI; NbExp=2; IntAct=EBI-15221122, EBI-446380;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in leaves. {ECO:0000269|PubMed:18718758}.
CC -!- INDUCTION: Expressed with a circadian rhythm showing a peak at dawn.
CC {ECO:0000269|PubMed:18718758}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. RAV
CC subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC079281; AAG50808.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30642.1; -; Genomic_DNA.
DR EMBL; AY091069; AAM13889.1; -; mRNA.
DR EMBL; AY122941; AAM67474.1; -; mRNA.
DR PIR; A86386; A86386.
DR RefSeq; NP_173927.1; NM_102367.3.
DR PDB; 7ET4; X-ray; 2.70 A; A/D/G/J=50-170.
DR PDB; 7ET5; X-ray; 1.05 A; A=50-170.
DR PDB; 7ET6; X-ray; 2.70 A; A/D=186-309.
DR PDBsum; 7ET4; -.
DR PDBsum; 7ET5; -.
DR PDBsum; 7ET6; -.
DR AlphaFoldDB; Q9C6M5; -.
DR SMR; Q9C6M5; -.
DR BioGRID; 24380; 9.
DR DIP; DIP-59693N; -.
DR IntAct; Q9C6M5; 5.
DR STRING; 3702.AT1G25560.1; -.
DR PaxDb; Q9C6M5; -.
DR PRIDE; Q9C6M5; -.
DR ProteomicsDB; 236486; -.
DR EnsemblPlants; AT1G25560.1; AT1G25560.1; AT1G25560.
DR GeneID; 839143; -.
DR Gramene; AT1G25560.1; AT1G25560.1; AT1G25560.
DR KEGG; ath:AT1G25560; -.
DR Araport; AT1G25560; -.
DR TAIR; locus:2031185; AT1G25560.
DR eggNOG; ENOG502QRVI; Eukaryota.
DR HOGENOM; CLU_038898_0_0_1; -.
DR InParanoid; Q9C6M5; -.
DR OMA; DWKVQSG; -.
DR OrthoDB; 810704at2759; -.
DR PhylomeDB; Q9C6M5; -.
DR PRO; PR:Q9C6M5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C6M5; baseline and differential.
DR Genevisible; Q9C6M5; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0071456; P:cellular response to hypoxia; HEP:TAIR.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0048573; P:photoperiodism, flowering; IMP:TAIR.
DR CDD; cd00018; AP2; 1.
DR CDD; cd10017; B3_DNA; 1.
DR Gene3D; 2.40.330.10; -; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR003340; B3_DNA-bd.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR015300; DNA-bd_pseudobarrel_sf.
DR InterPro; IPR044800; LEC2-like.
DR PANTHER; PTHR31140; PTHR31140; 1.
DR Pfam; PF00847; AP2; 1.
DR Pfam; PF02362; B3; 1.
DR SMART; SM00380; AP2; 1.
DR SMART; SM01019; B3; 1.
DR SUPFAM; SSF101936; SSF101936; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
DR PROSITE; PS50863; B3; 1.
PE 1: Evidence at protein level;
KW 3D-structure; DNA-binding; Ethylene signaling pathway; Nucleus;
KW Reference proteome; Repressor; Transcription; Transcription regulation.
FT CHAIN 1..361
FT /note="AP2/ERF and B3 domain-containing transcription
FT repressor TEM1"
FT /id="PRO_0000290433"
FT DNA_BIND 71..126
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT DNA_BIND 195..306
FT /note="TF-B3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 75..77
FT /evidence="ECO:0007829|PDB:7ET5"
FT STRAND 83..89
FT /evidence="ECO:0007829|PDB:7ET5"
FT STRAND 92..101
FT /evidence="ECO:0007829|PDB:7ET5"
FT HELIX 102..117
FT /evidence="ECO:0007829|PDB:7ET5"
FT HELIX 118..120
FT /evidence="ECO:0007829|PDB:7ET5"
FT HELIX 134..140
FT /evidence="ECO:0007829|PDB:7ET5"
FT HELIX 144..152
FT /evidence="ECO:0007829|PDB:7ET5"
FT HELIX 156..163
FT /evidence="ECO:0007829|PDB:7ET5"
FT STRAND 191..198
FT /evidence="ECO:0007829|PDB:7ET6"
FT TURN 201..204
FT /evidence="ECO:0007829|PDB:7ET6"
FT STRAND 210..212
FT /evidence="ECO:0007829|PDB:7ET6"
FT HELIX 214..220
FT /evidence="ECO:0007829|PDB:7ET6"
FT TURN 223..226
FT /evidence="ECO:0007829|PDB:7ET6"
FT STRAND 240..245
FT /evidence="ECO:0007829|PDB:7ET6"
FT STRAND 251..259
FT /evidence="ECO:0007829|PDB:7ET6"
FT TURN 260..263
FT /evidence="ECO:0007829|PDB:7ET6"
FT STRAND 264..267
FT /evidence="ECO:0007829|PDB:7ET6"
FT HELIX 271..278
FT /evidence="ECO:0007829|PDB:7ET6"
FT STRAND 285..293
FT /evidence="ECO:0007829|PDB:7ET6"
FT STRAND 298..303
FT /evidence="ECO:0007829|PDB:7ET6"
SQ SEQUENCE 361 AA; 40558 MW; 52DB2D42DAD3042B CRC64;
MEYSCVDDSS TTSESLSIST TPKPTTTTEK KLSSPPATSM RLYRMGSGGS SVVLDSENGV
ETESRKLPSS KYKGVVPQPN GRWGAQIYEK HQRVWLGTFN EEEEAASSYD IAVRRFRGRD
AVTNFKSQVD GNDAESAFLD AHSKAEIVDM LRKHTYADEF EQSRRKFVNG DGKRSGLETA
TYGNDAVLRA REVLFEKTVT PSDVGKLNRL VIPKQHAEKH FPLPAMTTAM GMNPSPTKGV
LINLEDRTGK VWRFRYSYWN SSQSYVLTKG WSRFVKEKNL RAGDVVCFER STGPDRQLYI
HWKVRSSPVQ TVVRLFGVNI FNVSNEKPND VAVECVGKKR SREDDLFSLG CSKKQAIINI
L
