RAX1_SCHPO
ID RAX1_SCHPO Reviewed; 343 AA.
AC Q9P7S8;
DT 04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Protein rax1;
GN Name=rax1; ORFNames=SPAC23G3.05c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: May be involved in cell polarization and division.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000305};
CC Multi-pass membrane protein {ECO:0000305}.
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DR EMBL; CU329670; CAB72230.1; -; Genomic_DNA.
DR PIR; T50179; T50179.
DR RefSeq; NP_593105.1; NM_001018502.2.
DR AlphaFoldDB; Q9P7S8; -.
DR BioGRID; 278271; 9.
DR STRING; 4896.SPAC23G3.05c.1; -.
DR iPTMnet; Q9P7S8; -.
DR MaxQB; Q9P7S8; -.
DR PaxDb; Q9P7S8; -.
DR PRIDE; Q9P7S8; -.
DR EnsemblFungi; SPAC23G3.05c.1; SPAC23G3.05c.1:pep; SPAC23G3.05c.
DR GeneID; 2541778; -.
DR KEGG; spo:SPAC23G3.05c; -.
DR PomBase; SPAC23G3.05c; -.
DR VEuPathDB; FungiDB:SPAC23G3.05c; -.
DR eggNOG; ENOG502QRI8; Eukaryota.
DR HOGENOM; CLU_029881_1_1_1; -.
DR InParanoid; Q9P7S8; -.
DR OMA; VYSWFGV; -.
DR PhylomeDB; Q9P7S8; -.
DR Reactome; R-SPO-983231; Factors involved in megakaryocyte development and platelet production.
DR PRO; PR:Q9P7S8; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; ISS:PomBase.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0008104; P:protein localization; IBA:GO_Central.
DR Gene3D; 1.10.167.10; -; 1.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR Pfam; PF00615; RGS; 1.
DR SUPFAM; SSF48097; SSF48097; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cell membrane; Endoplasmic reticulum; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..343
FT /note="Protein rax1"
FT /id="PRO_0000353802"
FT TOPO_DOM 1..235
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 236..256
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 257..263
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 264..284
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 285..317
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 318..338
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 339..343
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT DOMAIN 109..228
FT /note="RGS"
SQ SEQUENCE 343 AA; 39695 MW; 388A8D67831FD9B7 CRC64;
MASAPRVSEV LTKKNLPPLS LYNFYIYIRD EENAIEFLDL FLDIMLHKFL FREHIRGLYK
AGVTSTSLNT ESSSTLGPHH FTRFRSASLS LEDLSTVYWP NFGPLLLEEL SNEQTINSSD
LLLSKDRAAY LKNLLTSNIQ SLTQESTVIS KEQVKMFTQI IIEKYFNPAS PHEVMLPPQL
VQPILDCKEH QRQDELRLFE DVETYLLNFL LKPAYYRFLN HKFKHNLNPL TCTGRFIIGY
VSTFAAYWLG FCGIFLDYSR RKRVWTLLPF AFGFYNLICT WSKHDPVLAL LGYSEVKPFH
YEKVLQPSIR LSLNRRAIFV LSIIVLIVGA NTAIFSCVPS IRL
