RAX2_ARATH
ID RAX2_ARATH Reviewed; 298 AA.
AC Q9SJL7; A5YZ54; A5YZ55; A5YZ66; Q6R0A1; Q9ZTE4;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 154.
DE RecName: Full=Transcription factor RAX2;
DE AltName: Full=Myb-related protein 38;
DE Short=AtMYB38;
DE AltName: Full=Protein REGULATOR OF AXILLARY MERISTEMS 2;
GN Name=RAX2; Synonyms=MYB38; OrderedLocusNames=At2g36890; ORFNames=T1J8.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Qu L.-J., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: a genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 55-298.
RC STRAIN=cv. Columbia;
RX PubMed=9839469; DOI=10.1046/j.1365-313x.1998.00278.x;
RA Kranz H.D., Denekamp M., Greco R., Jin H.-L., Leyva A., Meissner R.C.,
RA Petroni K., Urzainqui A., Bevan M., Martin C., Smeekens S., Tonelli C.,
RA Paz-Ares J., Weisshaar B.;
RT "Towards functional characterisation of the members of the R2R3-MYB gene
RT family from Arabidopsis thaliana.";
RL Plant J. 16:263-276(1998).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 124-268, AND VARIANTS ASP-175;
RP LYS-188; ASP-244 AND SER-256.
RC STRAIN=cv. Ag-0, cv. An-1, cv. Br-0, cv. C24, cv. Ct-1, cv. Cvi-1,
RC cv. Edi-0, cv. Ga-0, cv. Kas-1, cv. Kin-0, cv. Landsberg erecta, cv. Ll-0,
RC cv. Lz-0, cv. Ms-0, cv. Mt-0, cv. Nd-1, cv. Nok-3, cv. Oy-0, cv. Se-0,
RC cv. Sorbo, cv. Tsu-1, cv. Van-0, cv. Wa-1, and cv. Wassilewskija;
RX PubMed=17435248; DOI=10.1534/genetics.107.071928;
RA Ehrenreich I.M., Stafford P.A., Purugganan M.D.;
RT "The genetic architecture of shoot branching in Arabidopsis thaliana: a
RT comparative assessment of candidate gene associations vs. quantitative
RT trait locus mapping.";
RL Genetics 176:1223-1236(2007).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=11597504; DOI=10.1016/s1369-5266(00)00199-0;
RA Stracke R., Werber M., Weisshaar B.;
RT "The R2R3-MYB gene family in Arabidopsis thaliana.";
RL Curr. Opin. Plant Biol. 4:447-456(2001).
RN [7]
RP FUNCTION, AND TISSUE SPECIFICITY.
RX PubMed=16461581; DOI=10.1105/tpc.105.038745;
RA Mueller D., Schmitz G., Theres K.;
RT "Blind homologous R2R3 Myb genes control the pattern of lateral meristem
RT initiation in Arabidopsis.";
RL Plant Cell 18:586-597(2006).
RN [8]
RP GENE FAMILY.
RX PubMed=16463103; DOI=10.1007/s11103-005-2910-y;
RA Chen Y., Yang X., He K., Liu M., Li J., Gao Z., Lin Z., Zhang Y., Wang X.,
RA Qiu X., Shen Y., Zhang L., Deng X., Luo J., Deng X.-W., Chen Z., Gu H.,
RA Qu L.-J.;
RT "The MYB transcription factor superfamily of Arabidopsis: expression
RT analysis and phylogenetic comparison with the rice MYB family.";
RL Plant Mol. Biol. 60:107-124(2006).
CC -!- FUNCTION: Transcription activator (By similarity). Positively regulates
CC axillary meristems (AMs) formation and development, especially during
CC inflorescence. {ECO:0000250, ECO:0000269|PubMed:16461581}.
CC -!- INTERACTION:
CC Q9SJL7; P43254: COP1; NbExp=3; IntAct=EBI-2292310, EBI-301649;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- TISSUE SPECIFICITY: Ubiquitous, with higher levels in roots, flowers,
CC and shoot tips. Found in all cells of the shoot tips.
CC {ECO:0000269|PubMed:16461581}.
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DR EMBL; AY519577; AAS10047.1; -; mRNA.
DR EMBL; AC006922; AAD31574.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09315.1; -; Genomic_DNA.
DR EMBL; AF062880; AAC83602.1; -; mRNA.
DR EMBL; EF598636; ABR09096.1; -; Genomic_DNA.
DR EMBL; EF598637; ABR09097.1; -; Genomic_DNA.
DR EMBL; EF598638; ABR09098.1; -; Genomic_DNA.
DR EMBL; EF598639; ABR09099.1; -; Genomic_DNA.
DR EMBL; EF598640; ABR09100.1; -; Genomic_DNA.
DR EMBL; EF598641; ABR09101.1; -; Genomic_DNA.
DR EMBL; EF598642; ABR09102.1; -; Genomic_DNA.
DR EMBL; EF598643; ABR09103.1; -; Genomic_DNA.
DR EMBL; EF598644; ABR09104.1; -; Genomic_DNA.
DR EMBL; EF598645; ABR09105.1; -; Genomic_DNA.
DR EMBL; EF598646; ABR09106.1; -; Genomic_DNA.
DR EMBL; EF598647; ABR09107.1; -; Genomic_DNA.
DR EMBL; EF598648; ABR09108.1; -; Genomic_DNA.
DR EMBL; EF598649; ABR09109.1; -; Genomic_DNA.
DR EMBL; EF598650; ABR09110.1; -; Genomic_DNA.
DR EMBL; EF598651; ABR09111.1; -; Genomic_DNA.
DR EMBL; EF598652; ABR09112.1; -; Genomic_DNA.
DR EMBL; EF598653; ABR09113.1; -; Genomic_DNA.
DR EMBL; EF598654; ABR09114.1; -; Genomic_DNA.
DR EMBL; EF598655; ABR09115.1; -; Genomic_DNA.
DR EMBL; EF598656; ABR09116.1; -; Genomic_DNA.
DR EMBL; EF598657; ABR09117.1; -; Genomic_DNA.
DR EMBL; EF598658; ABR09118.1; -; Genomic_DNA.
DR EMBL; EF598659; ABR09119.1; -; Genomic_DNA.
DR PIR; H84785; H84785.
DR PIR; T51652; T51652.
DR RefSeq; NP_181226.1; NM_129245.3.
DR AlphaFoldDB; Q9SJL7; -.
DR SMR; Q9SJL7; -.
DR BioGRID; 3606; 2.
DR IntAct; Q9SJL7; 1.
DR STRING; 3702.AT2G36890.1; -.
DR PaxDb; Q9SJL7; -.
DR PRIDE; Q9SJL7; -.
DR ProteomicsDB; 236487; -.
DR EnsemblPlants; AT2G36890.1; AT2G36890.1; AT2G36890.
DR GeneID; 818262; -.
DR Gramene; AT2G36890.1; AT2G36890.1; AT2G36890.
DR KEGG; ath:AT2G36890; -.
DR Araport; AT2G36890; -.
DR TAIR; locus:2057931; AT2G36890.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_6_2_1; -.
DR InParanoid; Q9SJL7; -.
DR OMA; FIMSHQE; -.
DR PhylomeDB; Q9SJL7; -.
DR PRO; PR:Q9SJL7; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SJL7; baseline and differential.
DR Genevisible; Q9SJL7; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0009785; P:blue light signaling pathway; IMP:TAIR.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 1: Evidence at protein level;
KW Activator; Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW Repeat; Transcription; Transcription regulation.
FT CHAIN 1..298
FT /note="Transcription factor RAX2"
FT /id="PRO_0000312432"
FT DOMAIN 9..62
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 63..117
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 38..62
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 90..113
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT VARIANT 175
FT /note="G -> D (in strain: cv. Oy-0)"
FT /evidence="ECO:0000269|PubMed:17435248"
FT VARIANT 188
FT /note="N -> K (in strain: cv. An-1, cv. Ct-1, cv. Cvi-1 and
FT cv. Wassilewskija)"
FT /evidence="ECO:0000269|PubMed:17435248"
FT VARIANT 244
FT /note="H -> D (in strain: cv. An-1, cv. Ct-1, cv. Cvi-1 and
FT cv. Wassilewskija)"
FT /evidence="ECO:0000269|PubMed:17435248"
FT VARIANT 256
FT /note="T -> S (in strain: cv. An-1, cv. Ct-1, cv. Cvi-1 and
FT cv. Wassilewskija)"
FT /evidence="ECO:0000269|PubMed:17435248"
FT CONFLICT 141
FT /note="S -> P (in Ref. 1; AAS10047)"
FT /evidence="ECO:0000305"
FT CONFLICT 248
FT /note="Missing (in Ref. 4; AAC83602)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 298 AA; 34057 MW; 2554D975914869F8 CRC64;
MGRAPCCDKA NVKRGPWSPE EDAKLKDYIE KQGTGGNWIA LPHKAGLRRC GKSCRLRWLN
YLRPNIRHGD FTEEEDNIIY SLFASIGSRW SVIAAHLQGR TDNDIKNYWN TKLKKKLIAT
MAPPPHHHLA IATSSSSASP SSSSHYNMIN SLLPYNPSTN QLLTPHQGIM MTMMGQQQQL
FYQEDMGNLV NSPNRNNLIM SHQEDNQEQS TNKGIMLLSD VRSGSSTTST VTRVKMEHRD
HDDHHHHHEE DERSMTSVVM EDYGMEEIKQ LISSSCTSSN NSLWFDENKT EDKFMLYY
