RAX3_ARATH
ID RAX3_ARATH Reviewed; 310 AA.
AC Q9M2Y9; A5YZ78; A5YZ81; A5YZ92; A5YZ97;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 149.
DE RecName: Full=Transcription factor RAX3;
DE AltName: Full=Myb-related protein 84;
DE Short=AtMYB84;
DE AltName: Full=Protein REGULATOR OF AXILLARY MERISTEMS 3;
GN Name=RAX3; Synonyms=MYB84; OrderedLocusNames=At3g49690; ORFNames=T16K5.40;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Qu L.-J., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: a genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF Clones.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 99-283, AND VARIANTS ASP-131; ILE-229
RP AND VAL-238.
RC STRAIN=cv. Ag-0, cv. An-1, cv. Br-0, cv. C24, cv. Ct-1, cv. Cvi-1,
RC cv. Edi-0, cv. Ga-0, cv. Kas-1, cv. Kin-0, cv. Landsberg erecta, cv. Ll-0,
RC cv. Lz-0, cv. Ms-0, cv. Mt-0, cv. Nd-1, cv. Nok-3, cv. Oy-0, cv. Se-0,
RC cv. Sorbo, cv. Tsu-1, cv. Van-0, cv. Wa-1, and cv. Wassilewskija;
RX PubMed=17435248; DOI=10.1534/genetics.107.071928;
RA Ehrenreich I.M., Stafford P.A., Purugganan M.D.;
RT "The genetic architecture of shoot branching in Arabidopsis thaliana: a
RT comparative assessment of candidate gene associations vs. quantitative
RT trait locus mapping.";
RL Genetics 176:1223-1236(2007).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=11597504; DOI=10.1016/s1369-5266(00)00199-0;
RA Stracke R., Werber M., Weisshaar B.;
RT "The R2R3-MYB gene family in Arabidopsis thaliana.";
RL Curr. Opin. Plant Biol. 4:447-456(2001).
RN [7]
RP FUNCTION, DEVELOPMENTAL STAGE, AND TISSUE SPECIFICITY.
RX PubMed=16461581; DOI=10.1105/tpc.105.038745;
RA Mueller D., Schmitz G., Theres K.;
RT "Blind homologous R2R3 Myb genes control the pattern of lateral meristem
RT initiation in Arabidopsis.";
RL Plant Cell 18:586-597(2006).
RN [8]
RP GENE FAMILY.
RX PubMed=16463103; DOI=10.1007/s11103-005-2910-y;
RA Chen Y., Yang X., He K., Liu M., Li J., Gao Z., Lin Z., Zhang Y., Wang X.,
RA Qiu X., Shen Y., Zhang L., Deng X., Luo J., Deng X.-W., Chen Z., Gu H.,
RA Qu L.-J.;
RT "The MYB transcription factor superfamily of Arabidopsis: expression
RT analysis and phylogenetic comparison with the rice MYB family.";
RL Plant Mol. Biol. 60:107-124(2006).
CC -!- FUNCTION: Transcription activator (By similarity). Positively regulates
CC axillary meristems (AMs) formation and development, especially during
CC inflorescence. {ECO:0000250, ECO:0000269|PubMed:16461581}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:16461581}.
CC -!- DEVELOPMENTAL STAGE: Accumulates in an adaxial ball-shaped set of cells
CC in three to five cell layers around the L3 layer of the shoot apical
CC meristem (SAM) in youg plantlets. In the inflorescence meristem,
CC confined to the axils of flower primordia.
CC {ECO:0000269|PubMed:16461581}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY519597; AAS10067.1; -; mRNA.
DR EMBL; AL132965; CAB66907.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78577.1; -; Genomic_DNA.
DR EMBL; BT029224; ABJ98556.1; -; mRNA.
DR EMBL; EF598660; ABQ85360.1; -; Genomic_DNA.
DR EMBL; EF598661; ABQ85361.1; -; Genomic_DNA.
DR EMBL; EF598662; ABQ85362.1; -; Genomic_DNA.
DR EMBL; EF598663; ABQ85363.1; -; Genomic_DNA.
DR EMBL; EF598664; ABQ85364.1; -; Genomic_DNA.
DR EMBL; EF598665; ABQ85365.1; -; Genomic_DNA.
DR EMBL; EF598666; ABQ85366.1; -; Genomic_DNA.
DR EMBL; EF598667; ABQ85367.1; -; Genomic_DNA.
DR EMBL; EF598668; ABQ85368.1; -; Genomic_DNA.
DR EMBL; EF598669; ABQ85369.1; -; Genomic_DNA.
DR EMBL; EF598670; ABQ85370.1; -; Genomic_DNA.
DR EMBL; EF598671; ABQ85371.1; -; Genomic_DNA.
DR EMBL; EF598672; ABQ85372.1; -; Genomic_DNA.
DR EMBL; EF598673; ABQ85373.1; -; Genomic_DNA.
DR EMBL; EF598674; ABQ85374.1; -; Genomic_DNA.
DR EMBL; EF598675; ABQ85375.1; -; Genomic_DNA.
DR EMBL; EF598676; ABQ85376.1; -; Genomic_DNA.
DR EMBL; EF598677; ABQ85377.1; -; Genomic_DNA.
DR EMBL; EF598678; ABQ85378.1; -; Genomic_DNA.
DR EMBL; EF598679; ABQ85379.1; -; Genomic_DNA.
DR EMBL; EF598680; ABQ85380.1; -; Genomic_DNA.
DR EMBL; EF598681; ABQ85381.1; -; Genomic_DNA.
DR EMBL; EF598682; ABQ85382.1; -; Genomic_DNA.
DR EMBL; EF598683; ABQ85383.1; -; Genomic_DNA.
DR PIR; T46035; T46035.
DR RefSeq; NP_190538.1; NM_114829.4.
DR AlphaFoldDB; Q9M2Y9; -.
DR SMR; Q9M2Y9; -.
DR BioGRID; 9449; 7.
DR IntAct; Q9M2Y9; 6.
DR STRING; 3702.AT3G49690.1; -.
DR PaxDb; Q9M2Y9; -.
DR PRIDE; Q9M2Y9; -.
DR EnsemblPlants; AT3G49690.1; AT3G49690.1; AT3G49690.
DR GeneID; 824131; -.
DR Gramene; AT3G49690.1; AT3G49690.1; AT3G49690.
DR KEGG; ath:AT3G49690; -.
DR Araport; AT3G49690; -.
DR TAIR; locus:2097335; AT3G49690.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_6_2_1; -.
DR InParanoid; Q9M2Y9; -.
DR OMA; QEMMVMM; -.
DR OrthoDB; 1499244at2759; -.
DR PhylomeDB; Q9M2Y9; -.
DR PRO; PR:Q9M2Y9; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9M2Y9; baseline and differential.
DR Genevisible; Q9M2Y9; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 2: Evidence at transcript level;
KW Activator; Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW Repeat; Transcription; Transcription regulation.
FT CHAIN 1..310
FT /note="Transcription factor RAX3"
FT /id="PRO_0000312433"
FT DOMAIN 9..62
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 63..117
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND ?38..62
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND ?90..113
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT VARIANT 131
FT /note="E -> D (in strain: cv. Se-0)"
FT /evidence="ECO:0000269|PubMed:17435248"
FT VARIANT 229
FT /note="L -> I (in strain: cv. Cvi-1)"
FT /evidence="ECO:0000269|PubMed:17435248"
FT VARIANT 238
FT /note="L -> V (in strain: cv. Ct-1, cv. Edi-0 and cv. Ga-
FT 0)"
FT /evidence="ECO:0000269|PubMed:17435248"
SQ SEQUENCE 310 AA; 35578 MW; 647FB85D226CB6C3 CRC64;
MGRAPCCDKA NVKKGPWSPE EDAKLKSYIE NSGTGGNWIA LPQKIGLKRC GKSCRLRWLN
YLRPNIKHGG FSEEEENIIC SLYLTIGSRW SIIAAQLPGR TDNDIKNYWN TRLKKKLINK
QRKELQEACM EQQEMMVMMK RQHQQQQIQT SFMMRQDQTM FTWPLHHHNV QVPALFMNQT
NSFCDQEDVK PVLIKNMVKI EDQELEKTNP HHHQDSMTNA FDHLSFSQLL LDPNHNHLGS
GEGFSMNSIL SANTNSPLLN TSNDNQWFGN FQAETVNLFS GASTSTSADQ STISWEDISS
LVYSDSKQFF
