ID   AAEB_YERE8              Reviewed;         651 AA.
AC   A1JRH8;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeB {ECO:0000255|HAMAP-Rule:MF_01545};
DE            Short=pHBA efflux pump protein B {ECO:0000255|HAMAP-Rule:MF_01545};
GN   Name=aaeB {ECO:0000255|HAMAP-Rule:MF_01545}; OrderedLocusNames=YE3794;
OS   Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 /
OS   8081).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=393305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 13174 / 8081;
RX   PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA   Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA   Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA   Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA   Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA   Prentice M.B.;
RT   "The complete genome sequence and comparative genome analysis of the high
RT   pathogenicity Yersinia enterocolitica strain 8081.";
RL   PLoS Genet. 2:2039-2051(2006).
CC   -!- FUNCTION: Forms an efflux pump with AaeA. Could function as a metabolic
CC       relief valve, allowing to eliminate certain compounds when they
CC       accumulate to high levels in the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01545}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85)
CC       family. {ECO:0000255|HAMAP-Rule:MF_01545}.
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DR   EMBL; AM286415; CAL13818.1; -; Genomic_DNA.
DR   RefSeq; WP_011817278.1; NC_008800.1.
DR   RefSeq; YP_001007945.1; NC_008800.1.
DR   AlphaFoldDB; A1JRH8; -.
DR   SMR; A1JRH8; -.
DR   STRING; 393305.YE3794; -.
DR   EnsemblBacteria; CAL13818; CAL13818; YE3794.
DR   KEGG; yen:YE3794; -.
DR   PATRIC; fig|393305.7.peg.4041; -.
DR   eggNOG; COG1289; Bacteria.
DR   HOGENOM; CLU_027647_0_0_6; -.
DR   OMA; MITQACE; -.
DR   Proteomes; UP000000642; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046942; P:carboxylic acid transport; IEA:InterPro.
DR   HAMAP; MF_01545; AaeB; 1.
DR   InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR   InterPro; IPR023706; PHBA_efflux_pump_AaeB.
DR   PANTHER; PTHR30509:SF10; PTHR30509:SF10; 1.
DR   Pfam; PF04632; FUSC; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..651
FT                   /note="p-hydroxybenzoic acid efflux pump subunit AaeB"
FT                   /id="PRO_0000300569"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        119..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        368..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        405..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        429..449
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        460..480
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        481..501
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
SQ   SEQUENCE   651 AA;  72257 MW;  5E8A01D9C8157E8A CRC64;
     MTSPTFIRLR FAFKLSFAIV AALFLGFHLQ LETPRWSVLT AAIVAAGPAF AAGGEPFSGA
     IRHRGWLRII GTFIGCIGGL IIIVLTIRAP VLTLMLCCLW AGVCTWISSL VRVENSYAFG
     LAGYTALIII VTTGETPLLT PQFAVERCSE IVLGIVCAVM ADLLFSPRSI KQDIDRLVDK
     VLLDQYRLLQ LCIRPAEKTD IDRAWNDLVK NTTALNGMRS YLMMESSRWQ RCNRRLQVLH
     TESLTLITQA CETYLVLANH PDILTAELKA MLSEPAPTPA EIHQRMKTLR QFIAVSHSEA
     IPHTISSWVG AATRYLLLAK GIHTNSSISR VEEGILAGVV PVKHVSAEGH HAMINGLRTG
     VATAIGGLFW LWTGWTSGAG CMVMIAVVTS LAMRTPNPRM VAIDFLLGVI MALPIGALYF
     MFIIPATQQS MLLLCISLGL LAFIIGIEVQ KRRLGSLGTL ASTINIMVLS NPMEFNVSLF
     LDSALGQIVG CFVSLIVLLL IRDNAKDRTG RTLLNRFVYS AVSALTTNKA RRNENHLPAL
     YQQLNQLLMM FPGDIDKYRL ALTLIIAHQR LNKTEVPVNA ELSAFHKQIR YTADRVINAK
     NSQKRRYYFA RLLQELDQYQ QKLVDYQSPD AVTRPVKRLA DMLHKYQSAL I