ID   RBCR_ACIFR              Reviewed;         309 AA.
AC   Q06610;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=RuBisCO operon transcriptional regulator;
GN   Name=rbcR;
OS   Acidithiobacillus ferrooxidans (Thiobacillus ferrooxidans).
OC   Bacteria; Proteobacteria; Acidithiobacillia; Acidithiobacillales;
OC   Acidithiobacillaceae; Acidithiobacillus.
OX   NCBI_TaxID=920;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8432695; DOI=10.1128/jb.175.4.1019-1025.1993;
RA   Kusano T., Sugawara K.;
RT   "Specific binding of Thiobacillus ferrooxidans RbcR to the intergenic
RT   sequence between the rbc operon and the rbcR gene.";
RL   J. Bacteriol. 175:1019-1025(1993).
CC   -!- FUNCTION: Trans-acting transcriptional regulator of RuBisCO genes
CC       (rbcL1S1) expression.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; D11141; BAA01917.1; -; Genomic_DNA.
DR   PIR; B49698; B49698.
DR   AlphaFoldDB; Q06610; -.
DR   SMR; Q06610; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..309
FT                   /note="RuBisCO operon transcriptional regulator"
FT                   /id="PRO_0000105748"
FT   DOMAIN          6..63
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        23..42
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   309 AA;  33924 MW;  AADED43621D5A508 CRC64;
     MSIRHATLHQ LKIFAAVARH MSFARAAEEL HLTPPALSIQ VRQLAEAVGQ PLFDQIGKKI
     YLTAAGEALT SACHDILDRL EYFTQEIAAL QGLEKGSLKV ATLSTTKYFI PRMLGGFCTE
     HPGVATVLFI GNREVLLERL ARNQDDLYIL GQPPEHMNVV AEAFADNPLV VVARLDHPLT
     QEKDIEPSRL RDVPFILREP GSGTRLAAEK FFEQHGVILK TRMEFGSNEA VKQSVAGGLG
     ITVLSASTIR AELASGKLAI LDVRGFPLER KWYAVYPAGK RISPRTKAFM EYLFAASADG
     ENGPSLPKP