RBE_ARATH
ID RBE_ARATH Reviewed; 226 AA.
AC Q9LHS9;
DT 02-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT 02-FEB-2004, sequence version 2.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Probable transcriptional regulator RABBIT EARS;
GN Name=RBE; OrderedLocusNames=At5g06070; ORFNames=K16F4.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, TISSUE
RP SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX PubMed=14681191; DOI=10.1242/dev.00938;
RA Takeda S., Matsumoto N., Okada K.;
RT "RABBIT EARS, encoding a SUPERMAN-like zinc finger protein, regulates petal
RT development in Arabidopsis thaliana.";
RL Development 131:425-434(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable transcriptional regulator essential for petal
CC development. Required for the early development of the organ primordia
CC of the second whorl. Acts downstream of AP1 and PTL.
CC {ECO:0000269|PubMed:14681191}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:14681191}.
CC -!- TISSUE SPECIFICITY: Strongly expressed in inflorescences and flowers,
CC and weakly in siliques, seedlings and roots. In flowers, it is
CC expressed in petal primordia and their precursor cells. Also expressed
CC in the lateral root caps and the basal cells of lateral roots.
CC {ECO:0000269|PubMed:14681191}.
CC -!- DEVELOPMENTAL STAGE: Not expressed in the inflorescence meristem or in
CC the flowers at stages 1 and 2. First expressed in the precursor cells
CC of petal primordia in stage 3 flowers and in the developing petal
CC primordia up to stage 6. Not expressed at later stages.
CC {ECO:0000269|PubMed:14681191}.
CC -!- DOMAIN: Contains a slightly degenerated ERF-associated amphiphilic
CC repression (EAR) motif, which may be involved in the activity of
CC transcriptional repression.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM67167.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=BAA98196.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AB107371; BAC98433.1; -; mRNA.
DR EMBL; AP002030; BAA98196.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002688; AED90961.1; -; Genomic_DNA.
DR EMBL; AY088861; AAM67167.1; ALT_INIT; mRNA.
DR RefSeq; NP_568161.1; NM_120689.2.
DR AlphaFoldDB; Q9LHS9; -.
DR SMR; Q9LHS9; -.
DR BioGRID; 15773; 4.
DR IntAct; Q9LHS9; 4.
DR STRING; 3702.AT5G06070.1; -.
DR PaxDb; Q9LHS9; -.
DR PRIDE; Q9LHS9; -.
DR ProteomicsDB; 236990; -.
DR EnsemblPlants; AT5G06070.1; AT5G06070.1; AT5G06070.
DR GeneID; 830494; -.
DR Gramene; AT5G06070.1; AT5G06070.1; AT5G06070.
DR KEGG; ath:AT5G06070; -.
DR Araport; AT5G06070; -.
DR TAIR; locus:505006582; AT5G06070.
DR eggNOG; ENOG502QUGK; Eukaryota.
DR HOGENOM; CLU_068782_0_2_1; -.
DR InParanoid; Q9LHS9; -.
DR OMA; DVCNNNV; -.
DR OrthoDB; 1331939at2759; -.
DR PhylomeDB; Q9LHS9; -.
DR PRO; PR:Q9LHS9; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LHS9; baseline and differential.
DR Genevisible; Q9LHS9; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0048441; P:petal development; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR GO; GO:0009409; P:response to cold; IEP:TAIR.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR SMART; SM00355; ZnF_C2H2; 1.
DR SUPFAM; SSF57667; SSF57667; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; Differentiation; Flowering; Metal-binding; Nucleus;
KW Reference proteome; Repressor; Transcription; Transcription regulation;
KW Zinc; Zinc-finger.
FT CHAIN 1..226
FT /note="Probable transcriptional regulator RABBIT EARS"
FT /id="PRO_0000047838"
FT ZN_FING 55..77
FT /note="C2H2-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT REGION 80..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 212..216
FT /note="EAR-like (transcriptional repression)"
FT COMPBIAS 86..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 226 AA; 25338 MW; 2805E35A443CCE62 CRC64;
MMDRGECLMS MKLRPMVTRP SSDGTLFWPF REERAFASAE EYGGGGGCMW PPRSYSCSFC
GREFKSAQAL GGHMNVHRRD RARLKQQSLS PSSTDQATPP ECDRQQQVLD VGSKVLVQEE
TRKPNGTKRE ISDVCNNNVL ESSMKRYEHD NGEVKTDLSV GLLSTEFDPR KKQLINGSSS
SWKRAKTDVS RFPMMLGLVI GISEINGHHE ELDLELRLGA DPPKVN
