ID   RBF1_CANAX              Reviewed;         527 AA.
AC   Q00312;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Transcription factor RBF1;
DE   AltName: Full=RPG-box-binding factor 1;
DE   AltName: Full=Repressor-activator protein 1;
GN   Name=RBF1;
OS   Candida albicans (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=5476;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE, FUNCTION, AND
RP   DNA-BINDING.
RC   STRAIN=ATCC 10231 / CBS 6431 / CIP 48.72 / DSM 1386 / NBRC 1594;
RX   PubMed=9043119; DOI=10.1099/00221287-143-2-417;
RA   Ishii N., Yamamoto M., Lahm H.-W., Iizumi S., Yoshihara F., Nakayama H.,
RA   Arisawa M., Aoki Y.;
RT   "A DNA-binding protein from Candida albicans that binds to the RPG box of
RT   Saccharomyces cerevisiae and the telomeric repeat sequence of C.
RT   albicans.";
RL   Microbiology 143:417-427(1997).
RN   [2]
RP   CHARACTERIZATION.
RX   PubMed=9043120; DOI=10.1099/00221287-143-2-429;
RA   Ishii N., Yamamoto M., Yoshihara F., Arisawa M., Aoki Y.;
RT   "Biochemical and genetic characterization of Rbf1p, a putative
RT   transcription factor of Candida albicans.";
RL   Microbiology 143:429-435(1997).
CC   -!- FUNCTION: Transcriptional activator that binds to the RPG box and to
CC       telomeres. Involved in the regulation of the transition between yeast
CC       and filamentous forms and plays a role in virulence. Induces expression
CC       of HWP1, a major hyphal cell protein and virulence factor.
CC       {ECO:0000269|PubMed:9043119}.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome, telomere.
CC   -!- SIMILARITY: Belongs to the RBF1 family. {ECO:0000305}.
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DR   EMBL; D85862; BAA12888.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q00312; -.
DR   VEuPathDB; FungiDB:C6_02840C_A; -.
DR   VEuPathDB; FungiDB:CAWG_05080; -.
DR   GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Activator; Chromosome; Direct protein sequencing; DNA-binding; Nucleus;
KW   Telomere; Transcription; Transcription regulation.
FT   CHAIN           1..527
FT                   /note="Transcription factor RBF1"
FT                   /id="PRO_0000097185"
FT   DNA_BIND        160..300
FT                   /evidence="ECO:0000255"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          258..281
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          328..365
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          395..433
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          470..527
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        262..281
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        332..365
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        395..431
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        470..493
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   527 AA;  59441 MW;  A0DD675F937A807D CRC64;
     MSSNKNQSDL NIPTNSASLK QKQRQQLGIK SEIGASTSDV YDPQVASYLS AGDSPSQFAN
     TALHHSNSVG YSASAAAAAA ELQHRAELQR RQQQLQQQEL QHQQEQLQQY RQAQAQAQAQ
     AQAQREHQQL QHAYQQQQQL HQLGQLSQQL AQPHLSQHEH VRDALTTDEF DTNEDLRSRY
     IENEIVKTFN SKAELVHFVK NELGPEERCK IVINSSKPKA VYFQCERSGS FRTTVKDATK
     RQRIAYTKRN KCAYRLVANL YPNEKDQKRK NKPDEPGHNE ENSRISEMWV LRMINPQHNH
     APDPINKKKR QKTSRTLVEK PINKPHHHHL LQQEQQQQQQ QQQQQQQQQQ QQQHNANSQA
     QQQAAQLQQQ MQQQLQASGL PTTPNYSELL GQLGQLSQQQ SQQQQLHHIP QQRQRTQSQQ
     SQQQPQQTAH GLDQPDAAVI AAIEASAAAA VASQGSPNVT AAAVAALQHT QGNEHDAQQQ
     QDRGGNNGGA IDSNVDPSLD PNVDPNVQAH DHSHGLRNSY GKRSGFL