RBFA_HAEIN
ID RBFA_HAEIN Reviewed; 128 AA.
AC P45141;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Ribosome-binding factor A {ECO:0000255|HAMAP-Rule:MF_00003};
GN Name=rbfA {ECO:0000255|HAMAP-Rule:MF_00003}; OrderedLocusNames=HI_1288;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
RN [2]
RP X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS), AND SUBUNIT.
RA Bonander N., Tordova M., Howard A.J., Eisenstein E., Gilliland G.L.;
RT "The 1.7-A crystal structure of HI1288 - ribosome binding factor A (rbfA),
RT a cold response protein.";
RL Submitted (JUL-2001) to the PDB data bank.
CC -!- FUNCTION: One of several proteins that assist in the late maturation
CC steps of the functional core of the 30S ribosomal subunit. Associates
CC with free 30S ribosomal subunits (but not with 30S subunits that are
CC part of 70S ribosomes or polysomes). Required for efficient processing
CC of 16S rRNA. May interact with the 5'-terminal helix region of 16S
CC rRNA. {ECO:0000255|HAMAP-Rule:MF_00003}.
CC -!- SUBUNIT: Monomer (Ref.2). Binds 30S ribosomal subunits, but not 50S
CC ribosomal subunits or 70S ribosomes. {ECO:0000255|HAMAP-Rule:MF_00003,
CC ECO:0000305|Ref.2}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00003}.
CC -!- SIMILARITY: Belongs to the RbfA family. {ECO:0000255|HAMAP-
CC Rule:MF_00003}.
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DR EMBL; L42023; AAC22937.1; -; Genomic_DNA.
DR PIR; A64170; A64170.
DR RefSeq; NP_439440.1; NC_000907.1.
DR RefSeq; WP_005694530.1; NC_000907.1.
DR PDB; 1JOS; X-ray; 1.70 A; A=1-128.
DR PDBsum; 1JOS; -.
DR AlphaFoldDB; P45141; -.
DR SMR; P45141; -.
DR STRING; 71421.HI_1288; -.
DR EnsemblBacteria; AAC22937; AAC22937; HI_1288.
DR KEGG; hin:HI_1288; -.
DR PATRIC; fig|71421.8.peg.1340; -.
DR eggNOG; COG0858; Bacteria.
DR HOGENOM; CLU_089475_5_0_6; -.
DR OMA; GDLQHCK; -.
DR PhylomeDB; P45141; -.
DR BioCyc; HINF71421:G1GJ1-1314-MON; -.
DR EvolutionaryTrace; P45141; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0043024; F:ribosomal small subunit binding; IBA:GO_Central.
DR GO; GO:0030490; P:maturation of SSU-rRNA; IEA:UniProtKB-UniRule.
DR GO; GO:0042254; P:ribosome biogenesis; IBA:GO_Central.
DR Gene3D; 3.30.300.20; -; 1.
DR HAMAP; MF_00003; RbfA; 1.
DR InterPro; IPR015946; KH_dom-like_a/b.
DR InterPro; IPR000238; RbfA.
DR InterPro; IPR023799; RbfA_dom_sf.
DR InterPro; IPR020053; Ribosome-bd_factorA_CS.
DR PANTHER; PTHR33515; PTHR33515; 1.
DR Pfam; PF02033; RBFA; 1.
DR SUPFAM; SSF89919; SSF89919; 1.
DR TIGRFAMs; TIGR00082; rbfA; 1.
DR PROSITE; PS01319; RBFA; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; Reference proteome; Ribosome biogenesis.
FT CHAIN 1..128
FT /note="Ribosome-binding factor A"
FT /id="PRO_0000102670"
FT HELIX 8..26
FT /evidence="ECO:0007829|PDB:1JOS"
FT TURN 30..32
FT /evidence="ECO:0007829|PDB:1JOS"
FT STRAND 35..42
FT /evidence="ECO:0007829|PDB:1JOS"
FT STRAND 48..56
FT /evidence="ECO:0007829|PDB:1JOS"
FT HELIX 61..73
FT /evidence="ECO:0007829|PDB:1JOS"
FT HELIX 75..86
FT /evidence="ECO:0007829|PDB:1JOS"
FT STRAND 93..98
FT /evidence="ECO:0007829|PDB:1JOS"
SQ SEQUENCE 128 AA; 14805 MW; 9E274DC1240D64DF CRC64;
MAREFKRSDR VAQEIQKEIA VILQREVKDP RIGMVTVSDV EVSSDLSYAK IFVTFLFDHD
EMAIEQGMKG LEKASPYIRS LLGKAMRLRI VPEIRFIYDQ SLVEGMRMSN LVTNVVREDE
KKHVEESN
