RBFA_MOUSE
ID RBFA_MOUSE Reviewed; 350 AA.
AC Q6P3B9;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Putative ribosome-binding factor A, mitochondrial;
DE Flags: Precursor;
GN Name=Rbfa;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Mammary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the RbfA family. {ECO:0000305}.
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DR EMBL; BC064066; AAH64066.1; -; mRNA.
DR CCDS; CCDS29364.1; -.
DR RefSeq; NP_954667.1; NM_199197.1.
DR AlphaFoldDB; Q6P3B9; -.
DR SMR; Q6P3B9; -.
DR BioGRID; 213020; 2.
DR STRING; 10090.ENSMUSP00000025462; -.
DR iPTMnet; Q6P3B9; -.
DR PhosphoSitePlus; Q6P3B9; -.
DR EPD; Q6P3B9; -.
DR MaxQB; Q6P3B9; -.
DR PaxDb; Q6P3B9; -.
DR PRIDE; Q6P3B9; -.
DR ProteomicsDB; 300252; -.
DR Antibodypedia; 23520; 87 antibodies from 15 providers.
DR Ensembl; ENSMUST00000025462; ENSMUSP00000025462; ENSMUSG00000024570.
DR GeneID; 68731; -.
DR KEGG; mmu:68731; -.
DR UCSC; uc008fsm.1; mouse.
DR CTD; 79863; -.
DR MGI; MGI:1915981; Rbfa.
DR VEuPathDB; HostDB:ENSMUSG00000024570; -.
DR eggNOG; KOG4700; Eukaryota.
DR GeneTree; ENSGT00390000011362; -.
DR HOGENOM; CLU_067827_0_0_1; -.
DR InParanoid; Q6P3B9; -.
DR OMA; VCGINHE; -.
DR OrthoDB; 1420734at2759; -.
DR PhylomeDB; Q6P3B9; -.
DR TreeFam; TF328637; -.
DR BioGRID-ORCS; 68731; 5 hits in 71 CRISPR screens.
DR ChiTaRS; Rbfa; mouse.
DR PRO; PR:Q6P3B9; -.
DR Proteomes; UP000000589; Chromosome 18.
DR RNAct; Q6P3B9; protein.
DR Bgee; ENSMUSG00000024570; Expressed in granulocyte and 190 other tissues.
DR ExpressionAtlas; Q6P3B9; baseline and differential.
DR Genevisible; Q6P3B9; MM.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.20; -; 1.
DR InterPro; IPR015946; KH_dom-like_a/b.
DR InterPro; IPR000238; RbfA.
DR InterPro; IPR023799; RbfA_dom_sf.
DR InterPro; IPR039212; RBFA_mitochondrial.
DR InterPro; IPR020053; Ribosome-bd_factorA_CS.
DR PANTHER; PTHR14725; PTHR14725; 1.
DR Pfam; PF02033; RBFA; 1.
DR SUPFAM; SSF89919; SSF89919; 1.
DR PROSITE; PS01319; RBFA; 1.
PE 2: Evidence at transcript level;
KW Mitochondrion; Reference proteome; rRNA processing; Transit peptide.
FT TRANSIT 1..41
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 42..350
FT /note="Putative ribosome-binding factor A, mitochondrial"
FT /id="PRO_0000030227"
FT REGION 203..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..219
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..350
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 350 AA; 39317 MW; 00FABFB0F1C2A580 CRC64;
MWAGVAGLRG SCAGLQALWG GHRAALLLGR SPALHTSVAS CGSKNLLKKF ASKTRKKFWY
EGPSLGSHLT PRPSKHEFLT KTTSKKTRKE DSIRLRVLNG LLYKSLTELL CTPQVSQEVY
DLNVELSKVS VTSDFSACRV YWKTGVSAEQ NKHTESVLQR SAAYMRHLLI SQQTLRNVPP
IVFVQDKRDL VLAEVDRLLA EADFGPPDER DDLDGLRNAD AQVPHDSPEP AAHPNLCGID
HEALNKQIME YKRKKERGLQ CQSLAPPSGR EQAPEPTRLL RKREKVRSRW QHRDASPRSF
LLGEEDEDED SSTEWECHAH EAEDDDDHQE EELGADRGAQ RGLCGKREQG
