RBFA_STRAG
ID RBFA_STRAG Reviewed; 116 AA.
AC Q9K333; Q9ZF19;
DT 01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2004, sequence version 2.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Ribosome-binding factor A {ECO:0000255|HAMAP-Rule:MF_00003};
GN Name=rbfA {ECO:0000255|HAMAP-Rule:MF_00003};
OS Streptococcus agalactiae.
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1311;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=3076 / Serotype Ib;
RX PubMed=6096856; DOI=10.1073/pnas.81.24.7787;
RA Sacerdot C., Dessen P., Hershey J.W.B., Plumbridge J.A.,
RA Grunberg-Manago M.;
RT "Sequence of the initiation factor IF2 gene: unusual protein features and
RT homologies with elongation factors.";
RL Proc. Natl. Acad. Sci. U.S.A. 81:7787-7791(1984).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=3076 / Serotype Ib;
RX PubMed=7535280; DOI=10.1101/gad.9.5.626;
RA Dammel C.S., Noller H.F.;
RT "Suppression of a cold-sensitive mutation in 16S rRNA by overexpression of
RT a novel ribosome-binding factor, RbfA.";
RL Genes Dev. 9:626-637(1995).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=3074, 3076 / Serotype Ib, 3098, 3114, 3163, 3164, 941, and
RC 949 / Serotype II;
RX PubMed=10878130; DOI=10.1099/00221287-146-7-1661;
RA Hedegaard J., Hauge M., Fage-Larsen J., Mortensen K.K., Kilian M.,
RA Sperling-Petersen H.U., Poulsen K.;
RT "Investigation of the translation-initiation factor IF2 gene, infB, as a
RT tool to study the population structure of Streptococcus agalactiae.";
RL Microbiology 146:1661-1670(2000).
CC -!- FUNCTION: One of several proteins that assist in the late maturation
CC steps of the functional core of the 30S ribosomal subunit. Associates
CC with free 30S ribosomal subunits (but not with 30S subunits that are
CC part of 70S ribosomes or polysomes). Required for efficient processing
CC of 16S rRNA. May interact with the 5'-terminal helix region of 16S
CC rRNA. {ECO:0000255|HAMAP-Rule:MF_00003}.
CC -!- SUBUNIT: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal
CC subunits or 70S ribosomes. {ECO:0000255|HAMAP-Rule:MF_00003}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00003}.
CC -!- SIMILARITY: Belongs to the RbfA family. {ECO:0000255|HAMAP-
CC Rule:MF_00003}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA05920.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CAC00486.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CAC00488.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CAC00490.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CAC00492.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CAC00494.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CAC00496.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CAC00498.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AJ003164; CAA05920.1; ALT_INIT; Genomic_DNA.
DR EMBL; AJ251499; CAC00498.1; ALT_INIT; Genomic_DNA.
DR EMBL; AJ251493; CAC00486.1; ALT_INIT; Genomic_DNA.
DR EMBL; AJ251494; CAC00488.1; ALT_INIT; Genomic_DNA.
DR EMBL; AJ251495; CAC00490.1; ALT_INIT; Genomic_DNA.
DR EMBL; AJ251496; CAC00492.1; ALT_INIT; Genomic_DNA.
DR EMBL; AJ251498; CAC00496.1; ALT_INIT; Genomic_DNA.
DR EMBL; AJ251497; CAC00494.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_000715537.1; NZ_WNJJ01000009.1.
DR RefSeq; WP_001273670.1; NZ_JAAADB010000018.1.
DR AlphaFoldDB; Q9K333; -.
DR SMR; Q9K333; -.
DR GeneID; 66885357; -.
DR OMA; GDLQHCK; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030490; P:maturation of SSU-rRNA; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.300.20; -; 1.
DR HAMAP; MF_00003; RbfA; 1.
DR InterPro; IPR015946; KH_dom-like_a/b.
DR InterPro; IPR000238; RbfA.
DR InterPro; IPR023799; RbfA_dom_sf.
DR InterPro; IPR020053; Ribosome-bd_factorA_CS.
DR PANTHER; PTHR33515; PTHR33515; 1.
DR Pfam; PF02033; RBFA; 1.
DR SUPFAM; SSF89919; SSF89919; 1.
DR TIGRFAMs; TIGR00082; rbfA; 1.
DR PROSITE; PS01319; RBFA; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Ribosome biogenesis.
FT CHAIN 1..116
FT /note="Ribosome-binding factor A"
FT /id="PRO_0000102741"
FT VARIANT 23
FT /note="L -> F (in strain: 941 and 3114)"
SQ SEQUENCE 116 AA; 13378 MW; 5F55F70A847656D2 CRC64;
MANHRIDRVG MEIKREVNEI LRLRVNDPRV QDVTITDVQM LGDLSMAKVF YTIHSTLASD
NQKAQIGLEK ATGTIKRELG KNLTMYKIPD LQFVKDESIE YGNKIDEMLR NLDKKD
