ID   RBGA_BACCR              Reviewed;         296 AA.
AC   Q819W8;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Ribosome biogenesis GTPase A {ECO:0000250|UniProtKB:O31743};
GN   Name=rbgA {ECO:0000250|UniProtKB:O31743};
GN   Synonyms=ylqF {ECO:0000250|UniProtKB:O31743}; OrderedLocusNames=BC_3836;
OS   Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC
OS   15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=226900;
RN   [1] {ECO:0000312|EMBL:AAP10758.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373
RC   / NCTC 2599 / NRRL B-3711 {ECO:0000312|EMBL:AAP10758.1};
RX   PubMed=12721630; DOI=10.1038/nature01582;
RA   Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V.,
RA   Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M.,
RA   Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G.,
RA   Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.C.;
RT   "Genome sequence of Bacillus cereus and comparative analysis with Bacillus
RT   anthracis.";
RL   Nature 423:87-91(2003).
CC   -!- FUNCTION: Essential protein that is required for a late step of 50S
CC       ribosomal subunit assembly. Has GTPase activity that is stimulated by
CC       interaction with the immature 50S ribosome subunit. Binds to the 23S
CC       rRNA. Required for the association of ribosomal proteins rplP and rpmA
CC       with the large subunit (By similarity). {ECO:0000250|UniProtKB:O31743}.
CC   -!- SUBUNIT: Interacts with ctc. Interacts with the immature 50S ribosome
CC       subunit. 2 molecules of rbgA bind to one 50S subunit (By similarity).
CC       {ECO:0000250|UniProtKB:O31743}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O31743,
CC       ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01058}.
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DR   EMBL; AE016877; AAP10758.1; -; Genomic_DNA.
DR   RefSeq; NP_833557.1; NC_004722.1.
DR   RefSeq; WP_000236704.1; NZ_CP034551.1.
DR   AlphaFoldDB; Q819W8; -.
DR   SMR; Q819W8; -.
DR   STRING; 226900.BC_3836; -.
DR   EnsemblBacteria; AAP10758; AAP10758; BC_3836.
DR   GeneID; 67508472; -.
DR   KEGG; bce:BC3836; -.
DR   PATRIC; fig|226900.8.peg.3955; -.
DR   HOGENOM; CLU_011106_1_0_9; -.
DR   OMA; GVLWPKF; -.
DR   Proteomes; UP000001417; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   Gene3D; 1.10.1580.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR023179; GTP-bd_ortho_bundle_sf.
DR   InterPro; IPR019991; GTP-bd_ribosome_bgen.
DR   InterPro; IPR016478; GTPase_MTG1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   PIRSF; PIRSF006230; MG442; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR03596; GTPase_YlqF; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; GTP-binding; Hydrolase; Nucleotide-binding; Reference proteome;
KW   Ribosome biogenesis; RNA-binding.
FT   CHAIN           1..296
FT                   /note="Ribosome biogenesis GTPase A"
FT                   /id="PRO_0000409880"
FT   DOMAIN          14..178
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
FT   BINDING         58..61
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:O31743"
FT   BINDING         130..135
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:O31743"
FT   BINDING         174
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:O31743"
SQ   SEQUENCE   296 AA;  33376 MW;  990842BB8887AF9E CRC64;
     MVIQWFPGHM AKARRQVTEK LKLIDVVIEL VDARLPLSSR NPMIDEIITH KPRLVVLNKA
     DMADDRLTKQ WIAYFKEKGH MAISINAQAG QGMKEIAAAC KVLVKEKFDK MVAKGIRPRA
     IRALIVGIPN VGKSTLINKL AKKNIAKTGD RPGVTTAQQW IKVGKEMELL DTPGILWPKF
     EDQLVGLRLA TTGAIKDSIL NLQDVAVYAL RFMEKHYPER LKERYNLNEI PEDIVELFDA
     IGKNRGCLMG GGMIDYDKTS ELVLRELRGG KLGKMTFETP EEFGEQVEDV EKIEEV