ID   RBGA_GEOSW              Reviewed;         283 AA.
AC   C5D8U8;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Ribosome biogenesis GTPase A {ECO:0000250|UniProtKB:O31743};
GN   Name=rbgA {ECO:0000250|UniProtKB:O31743}; OrderedLocusNames=GWCH70_1095;
OS   Geobacillus sp. (strain WCH70).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC   unclassified Geobacillus.
OX   NCBI_TaxID=471223;
RN   [1] {ECO:0000312|EMBL:ACS23955.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WCH70 {ECO:0000312|EMBL:ACS23955.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Brumm P., Mead D.A., Richardson P.;
RT   "Complete sequence of chromosome of Geopacillus sp. WCH70.";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for a late step of 50S ribosomal subunit assembly.
CC       Has GTPase activity. Binds to the 23S rRNA (By similarity).
CC       {ECO:0000250|UniProtKB:O31743}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O31743,
CC       ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01058}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001638; ACS23955.1; -; Genomic_DNA.
DR   AlphaFoldDB; C5D8U8; -.
DR   SMR; C5D8U8; -.
DR   STRING; 471223.GWCH70_1095; -.
DR   EnsemblBacteria; ACS23955; ACS23955; GWCH70_1095.
DR   KEGG; gwc:GWCH70_1095; -.
DR   eggNOG; COG1161; Bacteria.
DR   HOGENOM; CLU_011106_1_0_9; -.
DR   OMA; GVLWPKF; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1580.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR023179; GTP-bd_ortho_bundle_sf.
DR   InterPro; IPR019991; GTP-bd_ribosome_bgen.
DR   InterPro; IPR016478; GTPase_MTG1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   PIRSF; PIRSF006230; MG442; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR03596; GTPase_YlqF; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; GTP-binding; Hydrolase; Nucleotide-binding; Ribosome biogenesis;
KW   RNA-binding.
FT   CHAIN           1..283
FT                   /note="Ribosome biogenesis GTPase A"
FT                   /id="PRO_0000409885"
FT   DOMAIN          16..181
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
FT   BINDING         60..63
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:O31743"
FT   BINDING         133..138
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:O31743"
FT   BINDING         177
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:O31743"
SQ   SEQUENCE   283 AA;  31742 MW;  2B59E5E307FED313 CRC64;
     MHMTIQWFPG HMAKAKREVQ EKLKLIDIVF ELLDARIPLS SRNPMIHEIL GNKPRIVLLN
     KADMADETVT EQWIAYFERQ QLHALAIDAQ TGTGIRQIVS AAKEMLKDKF AKMAAKGIKN
     PRPMRALIVG IPNVGKSTLI NRLAGRNIAK TGDKPGVTKA QQWIKVGKEM ELLDTPGILW
     PKFEDEEVGL KLATTGAIKD TILNLQDVAV YALNFLKQHY PERLKERYSL DDIPGEIVAL
     FDAIGKRRGC LVSGGAVDYD KVSEIVLHDI RTEKLGRLSF ETP