ID   RBGA_MYCPN              Reviewed;         271 AA.
AC   P75135;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Probable ribosome biogenesis GTPase A;
GN   Name=rbgA; OrderedLocusNames=MPN_656; ORFNames=K05_orf271, MP186;
OS   Mycoplasma pneumoniae (strain ATCC 29342 / M129) (Mycoplasmoides
OS   pneumoniae).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=272634;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA   Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT   "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT   pneumoniae.";
RL   Nucleic Acids Res. 24:4420-4449(1996).
CC   -!- FUNCTION: Required for a late step of 50S ribosomal subunit assembly.
CC       Has GTPase activity. Binds to the 23S rRNA (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01058}.
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DR   EMBL; U00089; AAB95834.1; -; Genomic_DNA.
DR   PIR; S73512; S73512.
DR   RefSeq; NP_110345.1; NC_000912.1.
DR   RefSeq; WP_010875013.1; NC_000912.1.
DR   AlphaFoldDB; P75135; -.
DR   SMR; P75135; -.
DR   IntAct; P75135; 10.
DR   STRING; 272634.MPN_656; -.
DR   EnsemblBacteria; AAB95834; AAB95834; MPN_656.
DR   GeneID; 66608656; -.
DR   KEGG; mpn:MPN_656; -.
DR   PATRIC; fig|272634.6.peg.721; -.
DR   HOGENOM; CLU_011106_1_0_14; -.
DR   OMA; GVLWPKF; -.
DR   BioCyc; MPNE272634:G1GJ3-1048-MON; -.
DR   Proteomes; UP000000808; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1580.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR023179; GTP-bd_ortho_bundle_sf.
DR   InterPro; IPR019991; GTP-bd_ribosome_bgen.
DR   InterPro; IPR016478; GTPase_MTG1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   PIRSF; PIRSF006230; MG442; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR03596; GTPase_YlqF; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; GTP-binding; Hydrolase; Nucleotide-binding; Reference proteome;
KW   Ribosome biogenesis.
FT   CHAIN           1..271
FT                   /note="Probable ribosome biogenesis GTPase A"
FT                   /id="PRO_0000210615"
FT   DOMAIN          21..175
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
FT   BINDING         127..132
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         171
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   271 AA;  30514 MW;  A15D4842DBFB6A29 CRC64;
     MDTFTSAVKI NWFPGHMKKT HDQLKKLASS LDGVIEVVDA RAPTLTQNPE ITAYFTNKPK
     LTLALKADLA QTVANSNILW GTLKQGLQLK RLVIKKLQTL FQAKKNQLKA KGLLVHQFRL
     AVIGMPNVGK SSLINLLLNK NHLQVANRAG VTKSMSWNQI SSEFYLSDTP GVFFKRIDEM
     AVGYKLVLTN VIKREVVPLE DVGAFAFCYL SKHYPQLLPY EGTDFTEFLH KFAISRKLLQ
     KSNQLNINLA CELFVSELIN GKYGKLSFEL D