ID   RBIS_BOVIN              Reviewed;         100 AA.
AC   A8YXZ5;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 2.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Ribosomal biogenesis factor {ECO:0000305};
GN   Name=RBIS;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Trans-acting factor in ribosome biogenesis required for
CC       efficient 40S and 60S subunit production.
CC       {ECO:0000250|UniProtKB:Q8N0T1}.
CC   -!- SUBUNIT: Associates with the pre-60S ribosomal particles.
CC       {ECO:0000250|UniProtKB:Q8N0T1}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q8N0T1}.
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DR   EMBL; BC108159; AAI08160.1; -; mRNA.
DR   RefSeq; NP_001103538.1; NM_001110068.2.
DR   AlphaFoldDB; A8YXZ5; -.
DR   SMR; A8YXZ5; -.
DR   PRIDE; A8YXZ5; -.
DR   GeneID; 510007; -.
DR   KEGG; bta:510007; -.
DR   CTD; 401466; -.
DR   HOGENOM; CLU_152931_0_0_1; -.
DR   InParanoid; A8YXZ5; -.
DR   OrthoDB; 1613527at2759; -.
DR   TreeFam; TF330773; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; ISS:UniProtKB.
DR   InterPro; IPR031389; RBIS.
DR   PANTHER; PTHR35544; PTHR35544; 1.
DR   Pfam; PF15679; DUF4665; 1.
PE   3: Inferred from homology;
KW   Acetylation; Nucleus; Phosphoprotein; Reference proteome.
FT   CHAIN           1..100
FT                   /note="Ribosomal biogenesis factor"
FT                   /id="PRO_0000324603"
FT   MOD_RES         19
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8N0T1"
FT   MOD_RES         21
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8N0T1"
FT   MOD_RES         69
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8N0T1"
SQ   SEQUENCE   100 AA;  11456 MW;  37D727E9E8A27034 CRC64;
     MAKNKLRGPK SRNVFHIASQ KNFKAKNKAK PVTTNLKKIN IMNEEKVNRV NKAFVNVQKE
     LAHFAKSISL EPLQKELIPQ QRHESKPVNV DEATRLMALL