RBM38_CHICK
ID RBM38_CHICK Reviewed; 215 AA.
AC Q5ZJX4;
DT 25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=RNA-binding protein 38;
DE AltName: Full=RNA-binding motif protein 38;
GN Name=RBM38; ORFNames=RCJMB04_14l15;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: RNA-binding protein that specifically bind the 3'-UTR of some
CC transcripts, leading to maintain their stability. Also acts as a mRNA
CC splicing factor. May play a role in myogenic differentiation (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}. Nucleus
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RBM38 family. {ECO:0000305}.
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DR EMBL; AJ720310; CAG31969.1; -; mRNA.
DR RefSeq; NP_001292022.1; NM_001305093.1.
DR AlphaFoldDB; Q5ZJX4; -.
DR SMR; Q5ZJX4; -.
DR STRING; 9031.ENSGALP00000042182; -.
DR PaxDb; Q5ZJX4; -.
DR Ensembl; ENSGALT00000045333; ENSGALP00000042182; ENSGALG00000026081.
DR GeneID; 768866; -.
DR KEGG; gga:768866; -.
DR CTD; 55544; -.
DR VEuPathDB; HostDB:geneid_768866; -.
DR eggNOG; KOG0149; Eukaryota.
DR GeneTree; ENSGT00940000158489; -.
DR HOGENOM; CLU_065652_2_0_1; -.
DR InParanoid; Q5ZJX4; -.
DR OMA; PAAFDQY; -.
DR OrthoDB; 1579773at2759; -.
DR PhylomeDB; Q5ZJX4; -.
DR PRO; PR:Q5ZJX4; -.
DR Proteomes; UP000000539; Chromosome 20.
DR Bgee; ENSGALG00000026081; Expressed in skeletal muscle tissue and 13 other tissues.
DR ExpressionAtlas; Q5ZJX4; baseline and differential.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IBA:GO_Central.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0048255; P:mRNA stabilization; IBA:GO_Central.
DR GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IBA:GO_Central.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
DR PROSITE; PS50102; RRM; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Differentiation; mRNA processing; mRNA splicing; Nucleus;
KW Reference proteome; RNA-binding.
FT CHAIN 1..215
FT /note="RNA-binding protein 38"
FT /id="PRO_0000355183"
FT DOMAIN 11..88
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
SQ SEQUENCE 215 AA; 23453 MW; 4D82921C5125F804 CRC64;
MHTVQKDTTF TKIFVGGLPY HTTDSSLRKY FEVFGDIEEA VVITDRQTGK SRGYGFVTMA
DRAAAERACK DPNPIIDGRK ANVNLAYLGA KPRSIQTGFT IGVQQLHPAF IQRPFGLTPH
YVYPQAIIQP SVVIPTPVQS IASPYIDYTA ASQAYSQYTT AAYDQYPYAA SPAAGFVGYG
YTGAVQPPIT ASTPAAPATA FVQYQPQQLQ PDRMQ
