RBM43_MOUSE
ID RBM43_MOUSE Reviewed; 343 AA.
AC Q99J64;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 143.
DE RecName: Full=RNA-binding protein 43;
DE AltName: Full=RNA-binding motif protein 43;
GN Name=Rbm43;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Kidney;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=NMRI; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; AK002739; BAC25004.1; -; mRNA.
DR EMBL; BC003333; AAH03333.1; -; mRNA.
DR CCDS; CCDS16030.1; -.
DR RefSeq; NP_001135453.1; NM_001141981.1.
DR RefSeq; NP_001135454.1; NM_001141982.1.
DR RefSeq; NP_084519.1; NM_030243.4.
DR RefSeq; XP_006498403.1; XM_006498340.1.
DR RefSeq; XP_006498404.1; XM_006498341.1.
DR RefSeq; XP_006498405.1; XM_006498342.3.
DR RefSeq; XP_006498406.1; XM_006498343.3.
DR RefSeq; XP_006498407.1; XM_006498344.2.
DR RefSeq; XP_006498408.1; XM_006498345.1.
DR RefSeq; XP_011237487.1; XM_011239185.1.
DR RefSeq; XP_011237489.1; XM_011239187.1.
DR AlphaFoldDB; Q99J64; -.
DR SMR; Q99J64; -.
DR STRING; 10090.ENSMUSP00000099828; -.
DR PhosphoSitePlus; Q99J64; -.
DR EPD; Q99J64; -.
DR MaxQB; Q99J64; -.
DR PaxDb; Q99J64; -.
DR PeptideAtlas; Q99J64; -.
DR PRIDE; Q99J64; -.
DR ProteomicsDB; 255040; -.
DR Antibodypedia; 51960; 79 antibodies from 16 providers.
DR DNASU; 71684; -.
DR Ensembl; ENSMUST00000102767; ENSMUSP00000099828; ENSMUSG00000036249.
DR Ensembl; ENSMUST00000102768; ENSMUSP00000099829; ENSMUSG00000036249.
DR Ensembl; ENSMUST00000165313; ENSMUSP00000126129; ENSMUSG00000036249.
DR GeneID; 71684; -.
DR KEGG; mmu:71684; -.
DR UCSC; uc008jqk.2; mouse.
DR CTD; 375287; -.
DR MGI; MGI:1918934; Rbm43.
DR VEuPathDB; HostDB:ENSMUSG00000036249; -.
DR eggNOG; KOG4012; Eukaryota.
DR GeneTree; ENSGT00530000063686; -.
DR HOGENOM; CLU_067477_0_0_1; -.
DR InParanoid; Q99J64; -.
DR OMA; TTICLKN; -.
DR OrthoDB; 1476205at2759; -.
DR PhylomeDB; Q99J64; -.
DR TreeFam; TF335737; -.
DR BioGRID-ORCS; 71684; 0 hits in 71 CRISPR screens.
DR ChiTaRS; Rbm43; mouse.
DR PRO; PR:Q99J64; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q99J64; protein.
DR Bgee; ENSMUSG00000036249; Expressed in spermatid and 241 other tissues.
DR Genevisible; Q99J64; MM.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034463; RBM43.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR15225:SF8; PTHR15225:SF8; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
DR PROSITE; PS50102; RRM; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; RNA-binding.
FT CHAIN 1..343
FT /note="RNA-binding protein 43"
FT /id="PRO_0000264248"
FT DOMAIN 15..90
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
SQ SEQUENCE 343 AA; 38637 MW; 1CCF5B9E21374B16 CRC64;
MASAWKVKDP TVAERTVVVS GLPVGLLKDQ LVKCYFQDEG GHVEEVIYPS KSKGVAYIIF
KEKKVAQDFI RQKKHPPGSE PRLTVSHFSE KVFNYVMAIL DLSVFRTQIE LESLVVDLKK
KIPTLNFSPL GPSGKISVQG SFLAIMKLKQ ALISKAISPL ENNRKDAGER RNWNGENPRR
ILQKRENSAS ILGTFVAEPA GSPETLVLDT DIFLYLKHKC EFYHLTLSKY HVLCQERVDG
DVTTICLQDA QDGSCSGSVR HVKEFIEECA QEFHLELRKE LLVLEGMGDR EKRNIRQALE
ELGGRYPRVL TNVHSTHIDL IGPPSDTYLF KTQLMKSAGQ KVT