ID   RBM46_DANRE             Reviewed;         510 AA.
AC   Q08BH5;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Probable RNA-binding protein 46;
DE   AltName: Full=RNA-binding motif protein 46;
GN   Name=rbm46; ORFNames=zgc:153695;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BC124720; AAI24721.1; -; mRNA.
DR   RefSeq; NP_001073493.2; NM_001080024.2.
DR   AlphaFoldDB; Q08BH5; -.
DR   SMR; Q08BH5; -.
DR   STRING; 7955.ENSDARP00000099341; -.
DR   PaxDb; Q08BH5; -.
DR   GeneID; 566042; -.
DR   KEGG; dre:566042; -.
DR   CTD; 166863; -.
DR   ZFIN; ZDB-GENE-061013-298; rbm46.
DR   eggNOG; KOG0117; Eukaryota.
DR   InParanoid; Q08BH5; -.
DR   OrthoDB; 1384330at2759; -.
DR   PhylomeDB; Q08BH5; -.
DR   PRO; PR:Q08BH5; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   CDD; cd12484; RRM1_RBM46; 1.
DR   CDD; cd12492; RRM2_RBM46; 1.
DR   Gene3D; 3.30.70.330; -; 3.
DR   InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR034434; RBM46_RRM1.
DR   InterPro; IPR034435; RBM46_RRM2.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 3.
DR   SMART; SM00360; RRM; 3.
DR   SUPFAM; SSF54928; SSF54928; 3.
DR   TIGRFAMs; TIGR01648; hnRNP-R-Q; 1.
DR   PROSITE; PS50102; RRM; 3.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; RNA-binding.
FT   CHAIN           1..510
FT                   /note="Probable RNA-binding protein 46"
FT                   /id="PRO_0000305317"
FT   DOMAIN          45..123
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          125..207
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          220..292
FT                   /note="RRM 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          23..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   510 AA;  56959 MW;  709BCCA022A04B40 CRC64;
     MDSSKEAALL ALMDRTGYSM VQENGQRKFG GPPPGWEGPP PPRGREVFVG KIPRDMYEDE
     LVPVFEQAGH IYEFRLMMEF SGENRGYAFV MYTTREKAQR AIQLLDNYEI RPGKFIGVCV
     SLDNCRLFIG SIPKDKKKEE IQEEMMKVTE GVMDVIVYPS AVDRMKNRGF AFVEYESHKA
     AAMARRKLIP GTFQLWGHTI QVDWAEPEKE LDEETMQRVR VLYVRNLMLS TTEETLRSEF
     SQLKPGSVER VKKLTDYAFI HFYNREDALT ALESMNGKVI DGSPIEVTLA KPASKDGNKR
     FGPRNCHNGV TAAGGYGDSN FLFRTRNDMT IGAMGNGLNA HALSLPYAVD LDRCVYPFLP
     GSTLVPVSLN TVKPSQLSSA VSLLDYYCHK NDWSLPEYHL YSLAGQEGKV MLIYKVVISS
     TRRSFMPDKV CTILEDAKEL AAQNALWNLD CSSGSSLNVS PPAPSGSGFL SFGCRSLPYP
     AYPMASISPP LPISCSSAQR LFIPNQSSFL