ID   RBM46_MACFA             Reviewed;         485 AA.
AC   Q4R2Z0;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 2.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Probable RNA-binding protein 46;
DE   AltName: Full=RNA-binding motif protein 46;
GN   Name=RBM46; ORFNames=QtsA-21007;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAE02529.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AB179478; BAE02529.1; ALT_FRAME; mRNA.
DR   AlphaFoldDB; Q4R2Z0; -.
DR   SMR; Q4R2Z0; -.
DR   STRING; 9541.XP_005556182.1; -.
DR   eggNOG; KOG0117; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   CDD; cd19901; DSRM_RBM46; 1.
DR   CDD; cd12484; RRM1_RBM46; 1.
DR   CDD; cd12492; RRM2_RBM46; 1.
DR   Gene3D; 3.30.70.330; -; 3.
DR   InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR044462; RBM46_DSR.
DR   InterPro; IPR034434; RBM46_RRM1.
DR   InterPro; IPR034435; RBM46_RRM2.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 3.
DR   SMART; SM00360; RRM; 3.
DR   SUPFAM; SSF54928; SSF54928; 2.
DR   TIGRFAMs; TIGR01648; hnRNP-R-Q; 1.
DR   PROSITE; PS50102; RRM; 3.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; RNA-binding.
FT   CHAIN           1..485
FT                   /note="Probable RNA-binding protein 46"
FT                   /id="PRO_0000305316"
FT   DOMAIN          61..139
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          141..223
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          236..308
FT                   /note="RRM 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
SQ   SEQUENCE   485 AA;  55290 MW;  EEF597180189C663 CRC64;
     MNEENIDGTN GCSKVRTGTQ NEAALLALME KTGYNMVQEN GQRKFGGPPP GWEGPPPPRG
     CEVFVGKIPR DMYEDELVPV FERAGKIYEF RLMMEFSGEN RGYAFVMYTT KEEAQLAIRI
     LNNYEIRPGK FIGVCVSLDN CRLFIGAIPK EKKKEEILDE MKKVTEGVVD VIVYPSATDK
     TKNRGFAFVE YESHRAAAMA RRKLIPGTFQ LWGHTIQVDW ADPEKEVDEE TMQRVKVLYV
     RNLMISTTEE TIKAEFNKFK PGAVERVKKL RDYAFVHFFN REDAVAAMSV MNGKCIDGAS
     IEVTLAKPVN KENTWRQHLN GQISPNSENL IVFANKEESH PKTLGKLPTL PARLNGQHSP
     SPPEVERCTY PFYPGTKLTP ISMYSLKSNH FNSAVMHLDY YCNKNNWAPP EYYLYSTTSQ
     DGKVLLVYKI VIPAIANGSQ SYFMPDKLCT TLEDAKELAA QFTLLHLDRE RNLFSLDLCR
     RIWRK