ID   RBM46_XENTR             Reviewed;         534 AA.
AC   Q0P4R6;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Probable RNA-binding protein 46;
DE   AltName: Full=RNA-binding motif protein 46;
GN   Name=rbm46;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC121934; AAI21935.1; -; mRNA.
DR   RefSeq; NP_001072501.1; NM_001079033.1.
DR   RefSeq; XP_012820846.1; XM_012965392.2.
DR   AlphaFoldDB; Q0P4R6; -.
DR   SMR; Q0P4R6; -.
DR   STRING; 8364.ENSXETP00000050765; -.
DR   DNASU; 779956; -.
DR   GeneID; 779956; -.
DR   KEGG; xtr:779956; -.
DR   CTD; 166863; -.
DR   Xenbase; XB-GENE-1011216; rbm46.
DR   eggNOG; KOG0117; Eukaryota.
DR   InParanoid; Q0P4R6; -.
DR   OrthoDB; 1384330at2759; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000032344; Expressed in testis and 3 other tissues.
DR   ExpressionAtlas; Q0P4R6; baseline.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   CDD; cd19901; DSRM_RBM46; 1.
DR   CDD; cd12492; RRM2_RBM46; 1.
DR   Gene3D; 3.30.70.330; -; 3.
DR   InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR044462; RBM46_DSR.
DR   InterPro; IPR034435; RBM46_RRM2.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 3.
DR   SMART; SM00360; RRM; 3.
DR   SUPFAM; SSF54928; SSF54928; 3.
DR   TIGRFAMs; TIGR01648; hnRNP-R-Q; 1.
DR   PROSITE; PS50102; RRM; 3.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; RNA-binding.
FT   CHAIN           1..534
FT                   /note="Probable RNA-binding protein 46"
FT                   /id="PRO_0000305318"
FT   DOMAIN          61..139
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          141..223
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          236..308
FT                   /note="RRM 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
SQ   SEQUENCE   534 AA;  60167 MW;  0515CF42CE23528F CRC64;
     MEDNCTDMFN GCSKFDISIQ TQVALLALID NTGYTMVQVN GQRKFGGPPP GWEGPPPPRG
     CEVFVGKIPR DMYEDKLVPL FARAGKIYEF RLMMEFSGEN RGYAFVMYTN KEEALLAIRM
     LNNYEICQGK FIGVCVSLDN CRLFIGSIPQ EKRKEEILEE MKKVTEGVMD VIVYPSATDK
     TKNRGFAFVM YESHRAAAMA RRKLIPGPFQ LWGHTIKVAW ASPEKEVDEE TMQKVKVLYV
     RNLMMSTTEE TIKAEFNRYK PGVVERVKKI RDYAFVHFFR RDYAIAAMSV MNGRLIDGAR
     IEVTLAKPVN KEAAWRQNGN GHMNANSECL LNFANKEGSQ KALDMCSNVP AYLNNPNSPT
     FLEPETCTYP CIPGTKLTPI NLYSLKIHHF HSAVMHLEYF CYKNNWSFPE YYLYSTTGQD
     GKMLLAYKVI LPAITGNTNS YFMPDKLCSF VEDAKELAAQ FTLMHLDYSY HPTSGKNISL
     PSTAATSGTS GVLPYTPKPY SYSSYPSSPN VSLTNGGSVG KQLYVSNQAS YFSG