ID   RBM47_CANLF             Reviewed;         592 AA.
AC   Q9XSR3;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=RNA-binding protein 47;
DE   AltName: Full=RNA-binding motif protein 47;
GN   Name=RBM47; ORFNames=BC61;
OS   Canis lupus familiaris (Dog) (Canis familiaris).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis.
OX   NCBI_TaxID=9615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND SUBCELLULAR LOCATION.
RC   TISSUE=Thyroid;
RX   PubMed=10964405; DOI=10.1006/abio.2000.4674;
RA   Pichon B., Mercan D., Pouillon V., Christophe-Hobertus C., Christophe D.;
RT   "A method for the large-scale cloning of nuclear proteins and nuclear
RT   targeting sequences on a functional basis.";
RL   Anal. Biochem. 284:231-239(2000).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10964405}.
CC   -!- SIMILARITY: Belongs to the RRM RBM47 family. {ECO:0000305}.
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DR   EMBL; AJ388555; CAB46854.1; -; mRNA.
DR   RefSeq; NP_001002955.1; NM_001002955.1.
DR   AlphaFoldDB; Q9XSR3; -.
DR   SMR; Q9XSR3; -.
DR   STRING; 9612.ENSCAFP00000023389; -.
DR   PaxDb; Q9XSR3; -.
DR   Ensembl; ENSCAFT00040032935; ENSCAFP00040028658; ENSCAFG00040017744.
DR   Ensembl; ENSCAFT00845007224; ENSCAFP00845005751; ENSCAFG00845003991.
DR   GeneID; 403423; -.
DR   KEGG; cfa:403423; -.
DR   CTD; 54502; -.
DR   VEuPathDB; HostDB:ENSCAFG00845003991; -.
DR   eggNOG; KOG0117; Eukaryota.
DR   GeneTree; ENSGT00940000156979; -.
DR   InParanoid; Q9XSR3; -.
DR   OrthoDB; 1384330at2759; -.
DR   Proteomes; UP000002254; Chromosome 3.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0016554; P:cytidine to uridine editing; IEA:InterPro.
DR   CDD; cd12491; RRM2_RBM47; 1.
DR   CDD; cd12497; RRM3_RBM47; 1.
DR   Gene3D; 3.30.70.330; -; 3.
DR   InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR034442; RBM47.
DR   InterPro; IPR034440; RBM47_RRM2.
DR   InterPro; IPR034445; RBM47_RRM3.
DR   InterPro; IPR000504; RRM_dom.
DR   PANTHER; PTHR21245:SF6; PTHR21245:SF6; 1.
DR   Pfam; PF00076; RRM_1; 3.
DR   SMART; SM00360; RRM; 3.
DR   SUPFAM; SSF54928; SSF54928; 3.
DR   TIGRFAMs; TIGR01648; hnRNP-R-Q; 1.
DR   PROSITE; PS50102; RRM; 3.
PE   2: Evidence at transcript level;
KW   Methylation; Nucleus; Reference proteome; Repeat; RNA-binding.
FT   CHAIN           1..592
FT                   /note="RNA-binding protein 47"
FT                   /id="PRO_0000307854"
FT   DOMAIN          73..151
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          153..235
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          248..320
FT                   /note="RRM 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         397
FT                   /note="Asymmetric dimethylarginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:A0AV96"
FT   MOD_RES         397
FT                   /note="Omega-N-methylarginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:A0AV96"
FT   MOD_RES         408
FT                   /note="Asymmetric dimethylarginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:A0AV96"
FT   MOD_RES         408
FT                   /note="Omega-N-methylarginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:A0AV96"
SQ   SEQUENCE   592 AA;  63524 MW;  5952B93616CBE4E5 CRC64;
     MTAEDAAAAM SSDSAAGGAA SAKAPEGVAG APNEAALLAL LARTGYRMVQ ENGQRKYGGP
     PPGWEGPHPQ RGCEVFVGKI PRDVYEDELV PVFEAVGRIY ELRLMMDFDG KNRGYAFVTY
     CHKGEAKRAV RELNNHEIRP GRLLGVCCSV DNCRLFIGGI PKMKKREEIL EEIAKVTEGV
     LDVIVYASAA DKMKNRGFAF VEYESHRAAA MARRKLMPGR IQLWGHQIAV DWAEPEIDVD
     EDVMETVKIL YVRNLMIETT EDTIKKSFGQ FNPGCVERVK KIRDYAFVHF ASREDAVLAM
     NSLNGTELEG SCLEVTLAKP VDKEQYSRYQ KAAKGGGAAE AAAPQPGYVY SCDPYTLAYY
     GYPYNALIGP NRDYFVKAGS IRGRGRGAAG SRAPGPRGSY LGGYSAGRGI YSRYHEGKGK
     QQEKGYELVP NLEISAVNPV AIKPGTVAIP AIGAQYSMFQ AAPAPKMIED GKIHTMEHMI
     SPIAVQPDPA SAAAAAAAAA AAVIPAVSTP PPFQGRPITP VYTVAPNVQR IPAAGLYGAG
     YVPFAAPATA TLATLQKNAA AAAVYGGYAG YIPQAFPAAT IQVPIHDVYP TY