ID   RBM47_RAT               Reviewed;         590 AA.
AC   Q66H68;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=RNA-binding protein 47;
DE   AltName: Full=RNA-binding motif protein 47;
GN   Name=Rbm47;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRM RBM47 family. {ECO:0000305}.
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DR   EMBL; BC081995; AAH81995.1; -; mRNA.
DR   RefSeq; NP_001005882.1; NM_001005882.1.
DR   RefSeq; XP_006251011.1; XM_006250949.3.
DR   RefSeq; XP_006251012.1; XM_006250950.3.
DR   RefSeq; XP_006251013.1; XM_006250951.2.
DR   RefSeq; XP_006251014.1; XM_006250952.3.
DR   RefSeq; XP_006251016.1; XM_006250954.3.
DR   RefSeq; XP_006251017.1; XM_006250955.2.
DR   RefSeq; XP_008768374.1; XM_008770152.1.
DR   AlphaFoldDB; Q66H68; -.
DR   SMR; Q66H68; -.
DR   IntAct; Q66H68; 3.
DR   STRING; 10116.ENSRNOP00000003327; -.
DR   PaxDb; Q66H68; -.
DR   PRIDE; Q66H68; -.
DR   Ensembl; ENSRNOT00000003327; ENSRNOP00000003327; ENSRNOG00000002408.
DR   GeneID; 305340; -.
DR   KEGG; rno:305340; -.
DR   UCSC; RGD:1359713; rat.
DR   CTD; 54502; -.
DR   RGD; 1359713; Rbm47.
DR   eggNOG; KOG0117; Eukaryota.
DR   GeneTree; ENSGT00940000156979; -.
DR   HOGENOM; CLU_022960_4_2_1; -.
DR   InParanoid; Q66H68; -.
DR   OMA; APNIQRI; -.
DR   OrthoDB; 1384330at2759; -.
DR   PhylomeDB; Q66H68; -.
DR   TreeFam; TF314932; -.
DR   PRO; PR:Q66H68; -.
DR   Proteomes; UP000002494; Chromosome 14.
DR   Bgee; ENSRNOG00000002408; Expressed in jejunum and 15 other tissues.
DR   Genevisible; Q66H68; RN.
DR   GO; GO:0005634; C:nucleus; ISO:RGD.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; ISO:RGD.
DR   GO; GO:0016554; P:cytidine to uridine editing; ISO:RGD.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; ISO:RGD.
DR   CDD; cd12491; RRM2_RBM47; 1.
DR   CDD; cd12497; RRM3_RBM47; 1.
DR   Gene3D; 3.30.70.330; -; 3.
DR   InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR034442; RBM47.
DR   InterPro; IPR034440; RBM47_RRM2.
DR   InterPro; IPR034445; RBM47_RRM3.
DR   InterPro; IPR000504; RRM_dom.
DR   PANTHER; PTHR21245:SF6; PTHR21245:SF6; 1.
DR   Pfam; PF00076; RRM_1; 3.
DR   SMART; SM00360; RRM; 3.
DR   SUPFAM; SSF54928; SSF54928; 2.
DR   TIGRFAMs; TIGR01648; hnRNP-R-Q; 1.
DR   PROSITE; PS50102; RRM; 3.
PE   2: Evidence at transcript level;
KW   Methylation; Nucleus; Reference proteome; Repeat; RNA-binding.
FT   CHAIN           1..590
FT                   /note="RNA-binding protein 47"
FT                   /id="PRO_0000307858"
FT   DOMAIN          71..149
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          151..233
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          246..318
FT                   /note="RRM 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         396
FT                   /note="Asymmetric dimethylarginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:A0AV96"
FT   MOD_RES         396
FT                   /note="Omega-N-methylarginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:A0AV96"
FT   MOD_RES         407
FT                   /note="Asymmetric dimethylarginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:A0AV96"
FT   MOD_RES         407
FT                   /note="Omega-N-methylarginine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:A0AV96"
SQ   SEQUENCE   590 AA;  64094 MW;  9216AA3090B8EDF7 CRC64;
     MTAEDSTTAM NSDPTVGSST KVPEGVAGAP NEAALLALME RTGYNMVQEN GQRKYGGPPP
     GWEGPHPQRG CEVFVGKIPR DVYEDELVPV FETVGRIYEL RLMMDFDGKN RGYAFVMYCH
     KHEAKRAVRE LNNYEIRPGR LLGVCCSVDN CRLFIGGIPK MKKRGEILEE IAKVTEGVLN
     VIVYASAADK MKNRGFAFVE YESHRAAAMA RRKLMPGRIQ LWGHQIAVDW AEPEIDVDED
     VMQTVKILYV RNLMIETTEE TIKRSFGQFN PGCVERVKKI RDYAFVHFTS REDAVHAMNN
     LNGTELEGSC LEVTLAKPVD KEQYSRYQKA AKGGGGSAEA VAQQPSYVYS CDPYTLAYYG
     YPYNALIGPN RDYFVKTGSI RGRGRGAAGN RTPGPRGSYL GGYSAGRGIY SRYHEGKGKQ
     QEKGYELVPN LEISAVNPVA IKPGTVAIPA IGAQYSMFQA APAPKIIEDG KIHTMEHMIS
     PIAVQPDPAT AAAAAAAAAA AAVIPAVSTP PPFQGRPITP VYTVAPNVPR IPTAGIYGAS
     YVPFAAPATA TIATLQKNAA AAVYGGYAGY IPQAFPAALQ VPIHDVYQTY