ID   RBM48_BOVIN             Reviewed;         362 AA.
AC   A6QPE1;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 2.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=RNA-binding protein 48;
GN   Name=RBM48;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-110 (ISOFORM 1).
RX   PubMed=11282978; DOI=10.1101/gr.170101;
RA   Smith T.P.L., Grosse W.M., Freking B.A., Roberts A.J., Stone R.T.,
RA   Casas E., Wray J.E., White J., Cho J., Fahrenkrug S.C., Bennett G.L.,
RA   Heaton M.P., Laegreid W.W., Rohrer G.A., Chitko-McKown C.G., Pertea G.,
RA   Holt I., Karamycheva S., Liang F., Quackenbush J., Keele J.W.;
RT   "Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries
RT   and construction of a gene index for cattle.";
RL   Genome Res. 11:626-630(2001).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=A6QPE1-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=A6QPE1-2; Sequence=VSP_031784;
CC   -!- SIMILARITY: Belongs to the RBM48 family. {ECO:0000305}.
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DR   EMBL; BC149271; AAI49272.1; -; mRNA.
DR   EMBL; AW325666; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_001095324.2; NM_001101854.2. [A6QPE1-1]
DR   AlphaFoldDB; A6QPE1; -.
DR   SMR; A6QPE1; -.
DR   STRING; 9913.ENSBTAP00000024429; -.
DR   PaxDb; A6QPE1; -.
DR   PRIDE; A6QPE1; -.
DR   Ensembl; ENSBTAT00000024429; ENSBTAP00000024429; ENSBTAG00000018363. [A6QPE1-1]
DR   GeneID; 505408; -.
DR   KEGG; bta:505408; -.
DR   CTD; 84060; -.
DR   VEuPathDB; HostDB:ENSBTAG00000018363; -.
DR   eggNOG; ENOG502QSNB; Eukaryota.
DR   GeneTree; ENSGT00390000004541; -.
DR   HOGENOM; CLU_065720_0_0_1; -.
DR   InParanoid; A6QPE1; -.
DR   OMA; AKWRIIC; -.
DR   OrthoDB; 1117000at2759; -.
DR   TreeFam; TF328457; -.
DR   Proteomes; UP000009136; Chromosome 4.
DR   Bgee; ENSBTAG00000018363; Expressed in oocyte and 103 other tissues.
DR   GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   CDD; cd12442; RRM_RBM48; 1.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR039599; RBM48.
DR   InterPro; IPR034264; RBM48_RRM.
DR   PANTHER; PTHR20957; PTHR20957; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome; RNA-binding.
FT   CHAIN           1..362
FT                   /note="RNA-binding protein 48"
FT                   /id="PRO_0000321513"
FT   DOMAIN          46..124
FT                   /note="RRM"
FT   REGION          334..362
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        334..355
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         1..106
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|Ref.1"
FT                   /id="VSP_031784"
SQ   SEQUENCE   362 AA;  41206 MW;  2ABC91BBF0FDF39C CRC64;
     MASSGGQIGG VLDHHVQRAV CDSRAKYREG RRPRAVKVYT INLESWYLLI QGVPAVGAMK
     ELVERFALYG TIEQYNALDE YPAEDFTEVY LIKFLNLQSA RIAKRKMDEQ SFFGGLLHVC
     YAPEFETVEE TRKKLRERNA YVARMTKNKD HYMTKKHKDA KDFRGAFHSK TSGFPAASLN
     TSTGNSDLCL PYSSELPLCY FSPKCKCSSG ERVDRPSNSS QDGRNFDETL GRCDHCDSLQ
     KMQMKTLQNS LARPGTQKAL TPSEAVDRFM PRTTQLQERK RRREDDCKRE TLAEACTSSK
     EVMIGPQLPG IPKVDTHDGS WNTTASLIRE KLKEVISSVP KPPEDKVEDV HRSRPLKQRR
     RI