ID   RBM48_PONAB             Reviewed;         367 AA.
AC   Q5R4U2; Q5R935;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=RNA-binding protein 48;
GN   Name=RBM48;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the RBM48 family. {ECO:0000305}.
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DR   EMBL; CR859560; CAH91725.1; -; mRNA.
DR   EMBL; CR861149; CAH93224.1; -; mRNA.
DR   RefSeq; NP_001126896.1; NM_001133424.1.
DR   AlphaFoldDB; Q5R4U2; -.
DR   SMR; Q5R4U2; -.
DR   STRING; 9601.ENSPPYP00000019971; -.
DR   Ensembl; ENSPPYT00000052716; ENSPPYP00000034154; ENSPPYG00000017819.
DR   GeneID; 100173911; -.
DR   KEGG; pon:100173911; -.
DR   CTD; 84060; -.
DR   eggNOG; ENOG502QSNB; Eukaryota.
DR   GeneTree; ENSGT00390000004541; -.
DR   HOGENOM; CLU_065720_0_0_1; -.
DR   InParanoid; Q5R4U2; -.
DR   OMA; PLCYFAS; -.
DR   OrthoDB; 1117000at2759; -.
DR   TreeFam; TF328457; -.
DR   Proteomes; UP000001595; Chromosome 7.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   CDD; cd12442; RRM_RBM48; 1.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR039599; RBM48.
DR   InterPro; IPR034264; RBM48_RRM.
DR   PANTHER; PTHR20957; PTHR20957; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; RNA-binding.
FT   CHAIN           1..367
FT                   /note="RNA-binding protein 48"
FT                   /id="PRO_0000321516"
FT   DOMAIN          46..124
FT                   /note="RRM"
FT   REGION          217..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          277..303
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          339..367
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        220..234
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        278..295
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        339..361
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        63
FT                   /note="V -> A (in Ref. 1; CAH91725)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        271
FT                   /note="V -> A (in Ref. 1; CAH91725)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   367 AA;  41748 MW;  679CAE87E1C3247E CRC64;
     MASSGGELGS LFDHHVQRAV CDTRAKYREG RRPRAVKVYT INLESQYLLI QGVPAVGVMK
     ELVERFALYG TIEQYNALDE YPAEDFTEVY LIKFMNLQSA RAAKRKMDEQ SFFGGLLHVC
     YAPEFETVEE TRKKLQVRKA YVVKTTENKD HYVTKKKLVT EHKDTEDFRQ DFHSEMSGFC
     KAALNTSAGN SNPYLPYSCE LPLCYFSSKC MCSSRGPVDR ASDSSKDGRN HHKTMGHYNH
     NGSLQKTQIN SFKNSVACPG AQKAVTSSEA VDRFMPRTTQ LQERKRRRED DRKLGTFLQT
     NPSGNEVMIG PLLPDISKVD MHDDSLNTTA NLIRHKLKEV ISSVPKPPED KPEDVNTSHP
     LKQRRRI