ID   RBMS1_BOVIN             Reviewed;         403 AA.
AC   Q3ZBP3;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=RNA-binding motif, single-stranded-interacting protein 1;
GN   Name=RBMS1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Heart ventricle;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Single-stranded DNA binding protein that interacts with the
CC       region upstream of the C-myc gene. Binds specifically to the DNA
CC       sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA
CC       replication (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC103186; AAI03187.1; -; mRNA.
DR   RefSeq; NP_001030438.1; NM_001035361.1.
DR   AlphaFoldDB; Q3ZBP3; -.
DR   SMR; Q3ZBP3; -.
DR   STRING; 9913.ENSBTAP00000006826; -.
DR   PaxDb; Q3ZBP3; -.
DR   PRIDE; Q3ZBP3; -.
DR   GeneID; 526135; -.
DR   KEGG; bta:526135; -.
DR   CTD; 5937; -.
DR   eggNOG; KOG4733; Eukaryota.
DR   HOGENOM; CLU_016278_2_0_1; -.
DR   InParanoid; Q3ZBP3; -.
DR   OrthoDB; 810893at2759; -.
DR   TreeFam; TF314644; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:1990904; C:ribonucleoprotein complex; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IBA:GO_Central.
DR   GO; GO:0008143; F:poly(A) binding; IBA:GO_Central.
DR   GO; GO:0008266; F:poly(U) RNA binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd12470; RRM1_MSSP1; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   InterPro; IPR002343; Hud_Sxl_RNA.
DR   InterPro; IPR034404; MSSP1_RRM1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 2.
DR   PRINTS; PR00961; HUDSXLRNA.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 2.
DR   PROSITE; PS50102; RRM; 2.
PE   2: Evidence at transcript level;
KW   DNA replication; DNA-binding; Nucleus; Phosphoprotein; Reference proteome;
KW   Repeat; RNA-binding.
FT   CHAIN           1..403
FT                   /note="RNA-binding motif, single-stranded-interacting
FT                   protein 1"
FT                   /id="PRO_0000287719"
FT   DOMAIN          62..135
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          141..226
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          30..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..56
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         208
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:P29558"
SQ   SEQUENCE   403 AA;  44112 MW;  B60F514FF2E3731C CRC64;
     MGKVWKQQMY PQYATYYYPQ YLQAKQSLVP AHPMAPPSPS TTSSNNNSSS SSNSGWDQLS
     KTNLYIRGLP PNTTDQDLVK LCQPYGKIVS TKAILDKTTN KCKGYGFVDF DSPAAAQKAV
     SALKASGVQA QMAKQQEQDP TNLYISNLPL SMDEQELENM LKPFGQVIST RILRDSSGTS
     RGVGFARMES TEKCEAVIGH FNGKFIKTPP GVSAPTEPLL CKFADGGQKK RQNPNKYIPN
     GRPWHREGEA GMTLTYDPTT AAIQNGFYPS PYSIATNRMI TQTSITPYIA SPVSAYQVQS
     PSWMQPQPYI LQHPGAVLTP SMEHTMSLQP ASMISPLAQQ MSHLSLGSTG TYMPATSAMQ
     GAYLPQYTHV QTAAVPVEEA SGQQQVTVET SNDHSPYTFQ PNK