RBP1A_ARATH
ID RBP1A_ARATH Reviewed; 228 AA.
AC Q9LMK7; O04149; Q9XHS1;
DT 27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 133.
DE RecName: Full=Ran-binding protein 1 homolog a;
DE AltName: Full=Ran-binding protein siRanBP;
GN Name=RANBP1A; Synonyms=SIRANBP; OrderedLocusNames=At1g07140;
GN ORFNames=F10K1.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], CHARACTERIZATION, TISSUE SPECIFICITY, AND
RP INTERACTION WITH RAN1; RAN2 AND RAN3.
RX PubMed=9025305; DOI=10.1046/j.1365-313x.1997.11010093.x;
RA Haizel T., Merkle T., Pay A., Fejes E., Nagy F.;
RT "Characterization of proteins that interact with the GTP-bound form of the
RT regulatory GTPase Ran in Arabidopsis.";
RL Plant J. 11:93-103(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RA Pih K.T., Jang H.J., Kang S.G., Piao H.L., Lim J.H., Jin J.B., Hwang I.H.;
RT "Isolation of cDNA encoding siRanBP protein.";
RL Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- SUBUNIT: Interacts with the GTP-bound form of RAN1, RAN2 and RAN3.
CC {ECO:0000269|PubMed:9025305}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Ubiquitous. Preferentially expressed in root tips
CC and gynoecium. {ECO:0000269|PubMed:9025305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD39835.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=CAA66045.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; X97377; CAA66045.1; ALT_FRAME; mRNA.
DR EMBL; AF057024; AAD39835.1; ALT_FRAME; mRNA.
DR EMBL; AC067971; AAF82206.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE28081.1; -; Genomic_DNA.
DR EMBL; AF370491; AAK43868.1; -; mRNA.
DR EMBL; AF410294; AAK95280.1; -; mRNA.
DR EMBL; AY097364; AAM19880.1; -; mRNA.
DR EMBL; BT002193; AAN72204.1; -; mRNA.
DR PIR; D86206; D86206.
DR RefSeq; NP_172194.1; NM_100588.4.
DR AlphaFoldDB; Q9LMK7; -.
DR SMR; Q9LMK7; -.
DR BioGRID; 22466; 8.
DR IntAct; Q9LMK7; 3.
DR STRING; 3702.AT1G07140.1; -.
DR iPTMnet; Q9LMK7; -.
DR MetOSite; Q9LMK7; -.
DR PaxDb; Q9LMK7; -.
DR PRIDE; Q9LMK7; -.
DR ProteomicsDB; 225960; -.
DR EnsemblPlants; AT1G07140.1; AT1G07140.1; AT1G07140.
DR GeneID; 837225; -.
DR Gramene; AT1G07140.1; AT1G07140.1; AT1G07140.
DR KEGG; ath:AT1G07140; -.
DR Araport; AT1G07140; -.
DR TAIR; locus:2007467; AT1G07140.
DR eggNOG; KOG0864; Eukaryota.
DR HOGENOM; CLU_067861_1_0_1; -.
DR InParanoid; Q9LMK7; -.
DR OMA; HLEQTGN; -.
DR OrthoDB; 1573143at2759; -.
DR PhylomeDB; Q9LMK7; -.
DR PRO; PR:Q9LMK7; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LMK7; baseline and differential.
DR Genevisible; Q9LMK7; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0005576; C:extracellular region; HDA:TAIR.
DR GO; GO:0005643; C:nuclear pore; IBA:GO_Central.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0050790; P:regulation of catalytic activity; IEA:GOC.
DR CDD; cd13179; RanBD_RanBP1; 1.
DR Gene3D; 2.30.29.30; -; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000156; Ran_bind_dom.
DR InterPro; IPR045255; RanBP1-like.
DR InterPro; IPR045256; RanBP1_RanBD.
DR PANTHER; PTHR23138; PTHR23138; 1.
DR Pfam; PF00638; Ran_BP1; 1.
DR SMART; SM00160; RanBD; 1.
DR PROSITE; PS50196; RANBD1; 1.
PE 1: Evidence at protein level;
KW mRNA transport; Nuclear pore complex; Nucleus; Protein transport;
KW Reference proteome; Translocation; Transport.
FT CHAIN 1..228
FT /note="Ran-binding protein 1 homolog a"
FT /id="PRO_0000097187"
FT DOMAIN 27..162
FT /note="RanBD1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00164"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..221
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 75
FT /note="K -> N (in Ref. 2; AAD39835)"
FT /evidence="ECO:0000305"
FT CONFLICT 86
FT /note="R -> P (in Ref. 2; AAD39835)"
FT /evidence="ECO:0000305"
FT CONFLICT 103
FT /note="V -> L (in Ref. 2; AAD39835)"
FT /evidence="ECO:0000305"
FT CONFLICT 132
FT /note="K -> Q (in Ref. 2; AAD39835)"
FT /evidence="ECO:0000305"
FT CONFLICT 137
FT /note="C -> Y (in Ref. 2; AAD39835)"
FT /evidence="ECO:0000305"
FT CONFLICT 194
FT /note="A -> L (in Ref. 1; CAA66045)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 228 AA; 25601 MW; 101E45421EF5B62F CRC64;
MATNEPEHEH RDEEEAGANE DEDTGAQVAP IVRLEEVAVT TGEEDEDAVL DLKSKLYRFD
KDANQWKERG AGTVKFLKHK NTGKIRLVMR QSKTLKICAN HFVKSGMSVQ EHVGNEKSCV
WHARDFADGE LKDELFCIRF ASIENCKTFM QKFKEVAESE EEKEESKDAA DTAGLLEKLT
VEETKTEEKT EAKAVETAKT EVKAEEKKES EAEKSGEAKK TEESGPST
