RBP1_ARATH
ID RBP1_ARATH Reviewed; 360 AA.
AC Q9C652; Q9SM01;
DT 26-JUN-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=RNA-binding protein 1;
DE Short=AtRBP1;
GN Name=RBP1; Synonyms=XF41; OrderedLocusNames=At1g58470; ORFNames=F9K23.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=10548732; DOI=10.1016/s0378-1119(99)00403-5;
RA Kato A., Suzuki M., Kuwahara A., Ooe H., Higano-Inaba K., Komeda Y.;
RT "Isolation and analysis of cDNA within a 300 kb Arabidopsis thaliana
RT genomic region located around the 100 map unit of chromosome 1.";
RL Gene 239:309-316(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, AND DEVELOPMENTAL
RP STAGE.
RC STRAIN=cv. Columbia;
RX PubMed=10805591; DOI=10.1093/pcp/41.3.282;
RA Suzuki M., Kato A., Komeda Y.;
RT "An RNA-binding protein, AtRBP1, is expressed in actively proliferative
RT regions in Arabidopsis thaliana.";
RL Plant Cell Physiol. 41:282-288(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: RNA binding protein. Can also bind in vitro to single-
CC stranded DNA. {ECO:0000269|PubMed:10805591}.
CC -!- TISSUE SPECIFICITY: Highly expressed in inflorescences and roots.
CC Detected in leaves and seedlings, but not in stems. Expressed in
CC vegetative shoot apex and root meristem, but not in root cap. Detected
CC in flower buds, junction of pedicels, joints of immature siliques and
CC pistil. {ECO:0000269|PubMed:10805591}.
CC -!- DEVELOPMENTAL STAGE: Expressed in joints of immature siliques,
CC decreases with maturation and not detected in the joints of mature
CC siliques. {ECO:0000269|PubMed:10805591}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA88269.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AB008022; BAA88269.1; ALT_FRAME; mRNA.
DR EMBL; AB077822; BAB83876.1; -; Genomic_DNA.
DR EMBL; AC082643; AAG50640.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33552.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM57927.1; -; Genomic_DNA.
DR EMBL; AY054536; AAK96727.1; -; mRNA.
DR EMBL; AY064643; AAL47356.1; -; mRNA.
DR PIR; F96618; F96618.
DR PIR; T52461; T52461.
DR RefSeq; NP_001320402.1; NM_001333838.1.
DR RefSeq; NP_176143.1; NM_104627.2.
DR AlphaFoldDB; Q9C652; -.
DR SMR; Q9C652; -.
DR BioGRID; 27441; 1.
DR IntAct; Q9C652; 1.
DR STRING; 3702.AT1G58470.1; -.
DR PaxDb; Q9C652; -.
DR PRIDE; Q9C652; -.
DR ProteomicsDB; 225948; -.
DR EnsemblPlants; AT1G58470.1; AT1G58470.1; AT1G58470.
DR EnsemblPlants; AT1G58470.2; AT1G58470.2; AT1G58470.
DR GeneID; 842216; -.
DR Gramene; AT1G58470.1; AT1G58470.1; AT1G58470.
DR Gramene; AT1G58470.2; AT1G58470.2; AT1G58470.
DR KEGG; ath:AT1G58470; -.
DR Araport; AT1G58470; -.
DR TAIR; locus:2037633; AT1G58470.
DR eggNOG; KOG0118; Eukaryota.
DR HOGENOM; CLU_012062_1_2_1; -.
DR InParanoid; Q9C652; -.
DR OMA; TEGANYD; -.
DR OrthoDB; 1565323at2759; -.
DR PhylomeDB; Q9C652; -.
DR PRO; PR:Q9C652; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C652; baseline and differential.
DR Genevisible; Q9C652; AT.
DR GO; GO:0003729; F:mRNA binding; IPI:TAIR.
DR GO; GO:0003727; F:single-stranded RNA binding; IDA:TAIR.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; SSF54928; 2.
DR PROSITE; PS50102; RRM; 2.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome; Repeat; RNA-binding.
FT CHAIN 1..360
FT /note="RNA-binding protein 1"
FT /id="PRO_0000422767"
FT DOMAIN 6..82
FT /note="RRM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 120..197
FT /note="RRM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT COILED 93..113
FT /evidence="ECO:0000255"
SQ SEQUENCE 360 AA; 40341 MW; 701EEB4545D8C46B CRC64;
MDYDRYKLFV GGIAKETSEE ALKQYFSRYG AVLEAVVAKE KVTGKPRGFG FVRFANDCDV
VKALRDTHFI LGKPVDVRKA IRKHELYQQP FSMQFLERKV QQMNGGLREM SSNGVTSRTK
KIFVGGLSSN TTEEEFKSYF ERFGRTTDVV VMHDGVTNRP RGFGFVTYDS EDSVEVVMQS
NFHELSDKRV EVKRAIPKEG IQSNNGNAVN IPPSYSSFQA TPYVPEQNGY GMVLQFPPPV
FGYHHNVQAV QYPYGYQFTA QVANVSWNNP IMQPTGFYCA PPHPTPPPTN NLGYIQYMNG
FDLSGTNISG YNPLAWPVTG DAAGALIHQF VDLKLDVHSQ AHQRMNGGNM GIPLQNGTYI
