ID   AAEX_ECO57              Reviewed;          67 AA.
AC   Q8X9E0; Q7AAF9;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 2.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Protein AaeX {ECO:0000255|HAMAP-Rule:MF_01546};
GN   Name=aaeX {ECO:0000255|HAMAP-Rule:MF_01546};
GN   OrderedLocusNames=Z4601, ECs4115;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01546};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01546}.
CC   -!- INDUCTION: Positively coregulated with aaeA and aaeB by AaeR.
CC       {ECO:0000255|HAMAP-Rule:MF_01546}.
CC   -!- SIMILARITY: Belongs to the AaeX family. {ECO:0000255|HAMAP-
CC       Rule:MF_01546}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG58370.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=BAB37538.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE005174; AAG58370.1; ALT_INIT; Genomic_DNA.
DR   EMBL; BA000007; BAB37538.1; ALT_INIT; Genomic_DNA.
DR   PIR; C91143; C91143.
DR   PIR; F85988; F85988.
DR   RefSeq; NP_312142.2; NC_002695.1.
DR   RefSeq; WP_001310167.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; Q8X9E0; -.
DR   STRING; 155864.EDL933_4464; -.
DR   EnsemblBacteria; AAG58370; AAG58370; Z4601.
DR   EnsemblBacteria; BAB37538; BAB37538; ECs_4115.
DR   GeneID; 915547; -.
DR   KEGG; ece:Z4601; -.
DR   KEGG; ecs:ECs_4115; -.
DR   PATRIC; fig|386585.9.peg.4296; -.
DR   eggNOG; ENOG5032YJX; Bacteria.
DR   HOGENOM; CLU_188292_0_0_6; -.
DR   OMA; IYDLVWH; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01546; AaeX; 1.
DR   InterPro; IPR012451; DUF1656.
DR   Pfam; PF07869; DUF1656; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..67
FT                   /note="Protein AaeX"
FT                   /id="PRO_0000215049"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01546"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01546"
SQ   SEQUENCE   67 AA;  7794 MW;  FE90E275DFDD2183 CRC64;
     MSLFPVIVVF GLSFPPIFFE LLLSLAIFWL VCRVLVPTGI YDFVWHPALF NTALYCCLFY
     LISRLFV