RBPA_MYCTO
ID RBPA_MYCTO Reviewed; 111 AA.
AC P9WHJ4; L7N5Z6;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 35.
DE RecName: Full=RNA polymerase-binding protein RbpA {ECO:0000255|HAMAP-Rule:MF_01483};
GN Name=rbpA {ECO:0000255|HAMAP-Rule:MF_01483}; OrderedLocusNames=MT2110;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- FUNCTION: Binds to RNA polymerase (RNAP), stimulating transcription
CC from principal, but not alternative sigma factor promoters.
CC {ECO:0000255|HAMAP-Rule:MF_01483}.
CC -!- SUBUNIT: Forms a complex with the RNAP catalytic core and with free
CC principal sigma factors. {ECO:0000255|HAMAP-Rule:MF_01483}.
CC -!- SIMILARITY: Belongs to the RNA polymerase-binding protein RbpA family.
CC {ECO:0000255|HAMAP-Rule:MF_01483}.
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DR EMBL; AE000516; AAK46389.1; -; Genomic_DNA.
DR PIR; A70945; A70945.
DR RefSeq; WP_003410601.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WHJ4; -.
DR BMRB; P9WHJ4; -.
DR SMR; P9WHJ4; -.
DR EnsemblBacteria; AAK46389; AAK46389; MT2110.
DR GeneID; 45426029; -.
DR KEGG; mtc:MT2110; -.
DR PATRIC; fig|83331.31.peg.2276; -.
DR HOGENOM; CLU_134276_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0001000; F:bacterial-type RNA polymerase core enzyme binding; IEA:UniProtKB-UniRule.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR Gene3D; 2.20.28.270; -; 1.
DR HAMAP; MF_01483; RbpA; 1.
DR InterPro; IPR038638; RbpA_sf.
DR InterPro; IPR025182; RNApol-bd_RbpA.
DR Pfam; PF13397; RbpA; 1.
PE 3: Inferred from homology;
KW Transcription; Transcription regulation.
FT CHAIN 1..111
FT /note="RNA polymerase-binding protein RbpA"
FT /id="PRO_0000428174"
SQ SEQUENCE 111 AA; 12972 MW; EF75746152BB5CEB CRC64;
MADRVLRGSR LGAVSYETDR NHDLAPRQIA RYRTDNGEEF EVPFADDAEI PGTWLCRNGM
EGTLIEGDLP EPKKVKPPRT HWDMLLERRS IEELEELLKE RLELIRSRRR G