ID   RBP_BPLSK               Reviewed;         264 AA.
AC   O21886;
DT   02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   12-AUG-2020, entry version 58.
DE   RecName: Full=Receptor binding protein;
DE            Short=RBP;
DE   AltName: Full=Gene product 18;
DE            Short=Gp18;
OS   Lactococcus phage SK1 (Lactococcus lactis bacteriophage SK1).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Skunavirus.
OX   NCBI_TaxID=31532;
OH   NCBI_TaxID=1358; Lactococcus lactis.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9383189; DOI=10.1046/j.1365-2958.1997.5491926.x;
RA   Chandry P.S., Moore S.C., Boyce J.D., Davidson B.E., Hillier A.J.;
RT   "Analysis of the DNA sequence, gene expression, origin of replication and
RT   modular structure of the Lactococcus lactis lytic bacteriophage sk1.";
RL   Mol. Microbiol. 26:49-64(1997).
CC   -!- FUNCTION: Binds to the host phosphopolysaccharides at the onset of
CC       infection. Upon activation by calcium, the receptor binding proteins
CC       change their conformation, presenting their binding sites to the host,
CC       and a channel opens at the bottom of the baseplate for DNA ejection.
CC       {ECO:0000250|UniProtKB:Q71AW2}.
CC   -!- SUBUNIT: Homotrimer; found as an assembly of 6 homotrimers. Interacts
CC       with host phosphopolysaccharides; this allows the virus to bind the
CC       external cell wall layer. Interacts with the distal tail protein.
CC       {ECO:0000250|UniProtKB:Q71AW2}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:Q71AW2}. Note=Part
CC       of the baseplate. {ECO:0000250|UniProtKB:Q71AW2}.
CC   -!- DOMAIN: The C-terminus is involved in host receptor binding. Host-
CC       recognition domains point upwards, towards the capsid.
CC       {ECO:0000250|UniProtKB:Q71AW2}.
CC   -!- SIMILARITY: Belongs to the skunalikevirus receptor binding protein
CC       family. {ECO:0000305}.
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DR   EMBL; AF011378; AAB70057.1; -; Genomic_DNA.
DR   RefSeq; NP_044964.1; NC_001835.1.
DR   SMR; O21886; -.
DR   GeneID; 1261277; -.
DR   KEGG; vg:1261277; -.
DR   Proteomes; UP000000839; Genome.
DR   GO; GO:0098025; C:virus tail, baseplate; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0098670; P:entry receptor-mediated virion attachment to host cell; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   InterPro; IPR008982; Adenovirus_pIV-like_att.
DR   InterPro; IPR015027; Caudo_bapla_RBP.
DR   Pfam; PF08931; Caudo_bapla_RBP; 1.
DR   SUPFAM; SSF49835; SSF49835; 1.
PE   3: Inferred from homology;
KW   Host-virus interaction; Reference proteome; Viral attachment to host cell;
KW   Viral attachment to host entry receptor; Viral baseplate protein;
KW   Viral tail protein; Virion; Virus entry into host cell.
FT   CHAIN           1..264
FT                   /note="Receptor binding protein"
FT                   /id="PRO_0000438267"
FT   REGION          164..264
FT                   /note="Host receptor binding"
FT                   /evidence="ECO:0000250|UniProtKB:Q71AW2"
SQ   SEQUENCE   264 AA;  28692 MW;  CB1A730690706AD7 CRC64;
     MTIKNFTFFS PNSTEFPVGS NNDGKLYMML TGMDYRTIRR KDWSSPLNTA LNVQYTNTSI
     IAGGRYFELL NETVALKGNA VNYIHANIDL TRTANPVSLS AETSNNSNGV DINNGSGVLK
     VCFDIVTTSG TGVTSTKPTV QTSTLDSISV NDMTVSGSID VPVQTLTVEA GNGLDLQLTK
     KNNDLVIVRF FGSVSNIQKG WNMSGTWVDR PFRPAVVQSL VGHFAGRDTS FHIDINPNGS
     ITWWGESIDN TPIATRGNGS YFIK