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RBR_POPTR
ID   RBR_POPTR               Reviewed;        1035 AA.
AC   B9GLX8;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Retinoblastoma-related protein;
GN   Name=RBL901; ORFNames=POPTRDRAFT_547794;
OS   Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp.
OS   trichocarpa).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX   NCBI_TaxID=3694;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nisqually;
RX   PubMed=16973872; DOI=10.1126/science.1128691;
RA   Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I.,
RA   Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J.,
RA   Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W.,
RA   Brun A., Brunner A., Busov V., Campbell M., Carlson J., Chalot M.,
RA   Chapman J., Chen G.-L., Cooper D., Coutinho P.M., Couturier J., Covert S.,
RA   Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A.,
RA   dePamphilis C.W., Detter J., Dirks B., Dubchak I., Duplessis S.,
RA   Ehlting J., Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J.,
RA   Groover A., Gunter L., Hamberger B., Heinze B., Helariutta Y.,
RA   Henrissat B., Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S.,
RA   Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjaervi J., Karlsson J.,
RA   Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F.,
RA   Leebens-Mack J., Leple J.-C., Locascio P., Lou Y., Lucas S., Martin F.,
RA   Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O.,
RA   Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J.,
RA   Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J.,
RA   Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A.,
RA   Tsai C.-J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S.,
RA   Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y.,
RA   Rokhsar D.S.;
RT   "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).";
RL   Science 313:1596-1604(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nisqually;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Grigoriev I.V., Terry A., Salamov A.A., Otillar R., Lou Y., Lucas S.,
RA   Hammon N., Glavina del Rio T., Detter J., Kalin E., Tice H., Pitluck S.,
RA   Chapman J., Putnam N.H., Brunner A., Busov V., Campbell M., Chalot M.,
RA   Covert S., Davis J., DiFazio S., Gribskov M., Gunter L., Hamberger B.,
RA   Jansson S., Joshi C., Larimer F., Martin F., Napoli C., Nelson D.,
RA   Ralph S., Rombauts S., Rouze P., Schrader J., Tsai C., Vahala J.,
RA   Tuskan G., Rokhsar D.;
RL   Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulator of biological processes that recruits a histone
CC       deacetylase to control gene transcription. May play a role in the entry
CC       into mitosis, negatively regulating the cell proliferation. Formation
CC       of stable complexes with geminiviridae replication-associated proteins
CC       may create a cellular environment which favors viral DNA replication
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the retinoblastoma protein (RB) family.
CC       {ECO:0000305}.
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DR   EMBL; CM009290; EEE82535.1; -; Genomic_DNA.
DR   RefSeq; XP_002297730.1; XM_002297694.1.
DR   AlphaFoldDB; B9GLX8; -.
DR   SMR; B9GLX8; -.
DR   STRING; 3694.POPTR_0001s06870.1; -.
DR   EnsemblPlants; PNT52428; PNT52428; POPTR_001G031400v3.
DR   EnsemblPlants; PNT52429; PNT52429; POPTR_001G031400v3.
DR   GeneID; 7455806; -.
DR   Gramene; PNT52428; PNT52428; POPTR_001G031400v3.
DR   Gramene; PNT52429; PNT52429; POPTR_001G031400v3.
DR   KEGG; pop:7455806; -.
DR   eggNOG; KOG1010; Eukaryota.
DR   HOGENOM; CLU_015949_0_0_1; -.
DR   InParanoid; B9GLX8; -.
DR   OMA; AILCELH; -.
DR   Proteomes; UP000006729; Chromosome 1.
DR   ExpressionAtlas; B9GLX8; baseline and differential.
DR   GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005667; C:transcription regulator complex; IBA:GO_Central.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR002720; RB_A.
DR   InterPro; IPR002719; RB_B.
DR   InterPro; IPR028309; RB_fam.
DR   InterPro; IPR024599; RB_N.
DR   PANTHER; PTHR13742; PTHR13742; 1.
DR   Pfam; PF11934; DUF3452; 1.
DR   Pfam; PF01858; RB_A; 1.
DR   Pfam; PF01857; RB_B; 1.
DR   SMART; SM01367; DUF3452; 1.
DR   SMART; SM01368; RB_A; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
PE   3: Inferred from homology;
KW   Cell cycle; Nucleus; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..1035
FT                   /note="Retinoblastoma-related protein"
FT                   /id="PRO_0000380239"
FT   REGION          403..426
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          431..885
FT                   /note="Pocket"
FT                   /evidence="ECO:0000250"
FT   REGION          431..632
FT                   /note="Domain A"
FT                   /evidence="ECO:0000250"
FT   REGION          633..753
FT                   /note="Spacer"
FT                   /evidence="ECO:0000250"
FT   REGION          674..697
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          721..748
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          754..885
FT                   /note="Domain B"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   1035 AA;  114642 MW;  7A79E6F60156F2F3 CRC64;
     MSPAALKNME ENKTTVMTTS HSSNDGGETV KGYSDAVEVR FSDFCKSGLA LDENTCTQAI
     KLFKDTKHLL MTNVSSIGNG TSEEAERFWF AFVSYSVKRL SEKNRDDAQQ KSDDPGLTLC
     QILRLAKLNI VDFFKELPHF IVKAGPILSN IYGADWENRL EAKELQANFV HLSILSRHYK
     RACRELFLTS DASSDKQPAI SNEATHVSDH HRFGWLLFLA LRVHAFSRFK DLVTCTNGLV
     SVLAVLIIHV PVRFRNFSFN DSQWFVRKGD KGVDLLASLC NKYDTSEEVL RKSMETTNNL
     IANILKKKPH SASEYKNENL VNINPDGLIY YEDLMEESSL QSSLNILEKD YDDAIRNKAE
     LDERVFINEE DSLLGSGSVS AGSLNITGAK RKFDLISSPT KTITSPLSPH RSPASHANGI
     PGSANSKMAA TPVSTAMTTA KWLRTIISPL PSKPSAQLER FLVSCDKDVT NDVIRRAQII
     LEAIFPSSSL GERCVNGSLQ STNLMDNIWA EQRRLEALKL YYRVLESMCT AEAQILHATN
     LTSLLTNERF HRCMLACSAE LVVATYKTVT MLFPAVLERT GITAFDLSKV IESFIRHEES
     LPRELRRHLN SLEERLLDSM VWEKGSSLYN SLTVARPALS AEINRLGLLA EPMPSLDAIA
     MHINFSSGCL PPVPSLQKHE TSPGSGQNGD LRSPKRPCTD FRSVLVERNS FTSPVKDRLL
     GNLKSKLPPP PLQSAFASPT RPNPGGGGET CAETGINVFF TKINKLAAVR INGMIEKLQP
     SQQHIRENVY RLFQLILSHQ TSLFFNRHID QIILCCFYGV AKISKLNLTF REIIYNYRRQ
     PHCKTLVFRS VFVDWSSARH NGRTGQDHVD IITFYNEIFI PAAKPLLVDV GSAGTTVKAS
     NVPEVGNNKD GQCPASPKVS PFPSLPDMSP KKVSSAHNVY VSPLRSSKMD ALISNSSKSY
     YACVGESTHA YQSPSKDLNA INNRLNGNRK ARGTLNLDND VGLVSDSMVA NSLGLQNGNC
     ASTSGAALKS EQSDS
 
 
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