ID   RBSA1_THEMA             Reviewed;         520 AA.
AC   Q9WXX0;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 139.
DE   RecName: Full=Ribose import ATP-binding protein RbsA 1 {ECO:0000255|HAMAP-Rule:MF_01716};
DE            EC=7.5.2.7 {ECO:0000255|HAMAP-Rule:MF_01716};
GN   Name=rbsA1 {ECO:0000255|HAMAP-Rule:MF_01716}; OrderedLocusNames=TM_0115;
OS   Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
OS   / MSB8).
OC   Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX   NCBI_TaxID=243274;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8;
RX   PubMed=10360571; DOI=10.1038/20601;
RA   Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H.,
RA   Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A.,
RA   Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M.,
RA   Cotton M.D., Pratt M.S., Phillips C.A., Richardson D.L., Heidelberg J.F.,
RA   Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L.,
RA   Smith H.O., Venter J.C., Fraser C.M.;
RT   "Evidence for lateral gene transfer between Archaea and Bacteria from
RT   genome sequence of Thermotoga maritima.";
RL   Nature 399:323-329(1999).
CC   -!- FUNCTION: Part of the ABC transporter complex RbsABC involved in ribose
CC       import. Responsible for energy coupling to the transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_01716}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-ribose(out) + H2O = ADP + D-ribose(in) + H(+) +
CC         phosphate; Xref=Rhea:RHEA:29903, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:47013, ChEBI:CHEBI:456216; EC=7.5.2.7;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01716};
CC   -!- SUBUNIT: The complex is composed of an ATP-binding protein (RbsA), two
CC       transmembrane proteins (RbsC) and a solute-binding protein (RbsB).
CC       {ECO:0000255|HAMAP-Rule:MF_01716}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01716}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01716}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Ribose importer
CC       (TC 3.A.1.2.1) family. {ECO:0000255|HAMAP-Rule:MF_01716}.
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DR   EMBL; AE000512; AAD35209.1; -; Genomic_DNA.
DR   PIR; B72417; B72417.
DR   RefSeq; NP_227931.1; NC_000853.1.
DR   RefSeq; WP_004082693.1; NC_023151.1.
DR   AlphaFoldDB; Q9WXX0; -.
DR   SMR; Q9WXX0; -.
DR   STRING; 243274.THEMA_04230; -.
DR   TCDB; 3.A.1.2.18; the atp-binding cassette (abc) superfamily.
DR   EnsemblBacteria; AAD35209; AAD35209; TM_0115.
DR   KEGG; tma:TM0115; -.
DR   PATRIC; fig|243274.5.peg.113; -.
DR   eggNOG; COG1129; Bacteria.
DR   InParanoid; Q9WXX0; -.
DR   OMA; IKMLSGA; -.
DR   Proteomes; UP000008183; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015611; F:ABC-type D-ribose transporter activity; IEA:RHEA.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR   PROSITE; PS51254; RBSA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW   Nucleotide-binding; Reference proteome; Repeat; Sugar transport;
KW   Translocase; Transport.
FT   CHAIN           1..520
FT                   /note="Ribose import ATP-binding protein RbsA 1"
FT                   /id="PRO_0000261113"
FT   DOMAIN          15..256
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01716"
FT   DOMAIN          266..511
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01716"
FT   BINDING         47..54
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01716"
SQ   SEQUENCE   520 AA;  58633 MW;  3959BE91CA9DA2EB CRC64;
     MFPLLAFRGD RMEILKAKGI VKRFPGVVAV DNVDFEVYEN EIVSLIGENG AGKSTLIKIL
     TGVLKPDAGE ILVNGERVEF HSPVDAFKKG ISVIHQELNL CDNMTVAENI FLAYEAVRGQ
     KRTLSSRVDE NYMYTRSKEL LDLIGAKFSP DALVRNLTTA QRQMVEICKA LVKEPRIIFM
     DEPTSSLTVE ETERLFEIIE MLKSRGISVV FVSHRLDEVM RISDRIVVMR DGKRIGELKK
     GEFDVDTIIK MMVGREVEFF PHGIETRPGE IALEVRNLKW KDKVKNVSFE VRKGEVLGFA
     GLVGAGRTET MLLVFGVNQK ESGDIYVNGR KVEIKNPEDA IKMGIGLIPE DRKLQGLVLR
     MTVKDNIVLP SLKKISRWGL VLDERKEEEI SEDYVKRLSI KTPSIYQITE NLSGGNQQKV
     VLAKWLATNA DILIFDEPTR GIDVGAKAEI HRMIRELAAQ GKAVIMISSE LPEILNLSDR
     IVVMWEGEIT AVLDNREKRV TQEEIMYYAS GQKKQNGRVA