RBSA2_BURL3
ID RBSA2_BURL3 Reviewed; 506 AA.
AC Q398W2;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Ribose import ATP-binding protein RbsA 2 {ECO:0000255|HAMAP-Rule:MF_01716};
DE EC=7.5.2.7 {ECO:0000255|HAMAP-Rule:MF_01716};
GN Name=rbsA2 {ECO:0000255|HAMAP-Rule:MF_01716};
GN OrderedLocusNames=Bcep18194_B0885;
OS Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 /
OS R18194 / 383).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=482957;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A.,
RA Richardson P.;
RT "Complete sequence of chromosome 2 of Burkholderia sp. 383.";
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the ABC transporter complex RbsABC involved in ribose
CC import. Responsible for energy coupling to the transport system.
CC {ECO:0000255|HAMAP-Rule:MF_01716}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-ribose(out) + H2O = ADP + D-ribose(in) + H(+) +
CC phosphate; Xref=Rhea:RHEA:29903, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:47013, ChEBI:CHEBI:456216; EC=7.5.2.7;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01716};
CC -!- SUBUNIT: The complex is composed of an ATP-binding protein (RbsA), two
CC transmembrane proteins (RbsC) and a solute-binding protein (RbsB).
CC {ECO:0000255|HAMAP-Rule:MF_01716}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01716}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01716}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Ribose importer
CC (TC 3.A.1.2.1) family. {ECO:0000255|HAMAP-Rule:MF_01716}.
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DR EMBL; CP000152; ABB10999.1; -; Genomic_DNA.
DR RefSeq; WP_011354492.1; NC_007511.1.
DR AlphaFoldDB; Q398W2; -.
DR SMR; Q398W2; -.
DR EnsemblBacteria; ABB10999; ABB10999; Bcep18194_B0885.
DR GeneID; 45097241; -.
DR KEGG; bur:Bcep18194_B0885; -.
DR PATRIC; fig|482957.22.peg.4515; -.
DR HOGENOM; CLU_000604_92_3_4; -.
DR OMA; RIYTIFE; -.
DR OrthoDB; 551294at2; -.
DR Proteomes; UP000002705; Chromosome 2.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015611; F:ABC-type D-ribose transporter activity; IEA:RHEA.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS51254; RBSA; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Repeat; Sugar transport; Translocase; Transport.
FT CHAIN 1..506
FT /note="Ribose import ATP-binding protein RbsA 2"
FT /id="PRO_0000261051"
FT DOMAIN 5..241
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01716"
FT DOMAIN 251..498
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01716"
FT BINDING 37..44
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01716"
SQ SEQUENCE 506 AA; 55382 MW; 30191B4096A57543 CRC64;
MDTILRLSHI TKSFPGVKAL ADIDLEIARG EIHALLGENG AGKSTLMKIL CGIHQPDTGT
IEIDGTARHF SDYHDAVAAG VGIVFQEFSL IPHLDAVDNL FLGRELRNRW GARDRKRMRH
AAAAIFARLG VAIDLDAPIR ALSVAQQQFV EIGKALSLDA RILILDEPTA TLTPAEAEHL
FAIMRELKRQ GVAMIFISHH LDEIFAVCDR ITVLRDGQYV ATTDVARTDV EQLVRMMVGR
RIESSFPPKP VRAVDAPRVL EVNELQIERG GPVNRFTLHA GEILGFAGLV GSGRTETALA
VIGATRAHRK DVRVRGAAVK LADPADALRA GIGILPESRK TEGLVTSFSI RDNISLNNLG
KYRSMRWLID RRGEARTTHD VMRRVGVKAP SIHTEVATLS GGNQQKVVIA RWLNHHTSVL
IFDEPTRGID VGAKAEIYGL MRELTARGYA IIMISSELPE IVGMCDRVAV FRQGRIEATL
EGDEIDPDTV MTYATAGTRG ATHEPA
