RBSA2_STRCO
ID RBSA2_STRCO Reviewed; 517 AA.
AC Q9RDI1;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Ribose import ATP-binding protein RbsA 2 {ECO:0000255|HAMAP-Rule:MF_01716};
DE EC=7.5.2.7 {ECO:0000255|HAMAP-Rule:MF_01716};
GN Name=rbsA2 {ECO:0000255|HAMAP-Rule:MF_01716}; OrderedLocusNames=SCO2746;
GN ORFNames=SCC57A.17;
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145;
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- FUNCTION: Part of the ABC transporter complex RbsABC involved in ribose
CC import. Responsible for energy coupling to the transport system.
CC {ECO:0000255|HAMAP-Rule:MF_01716}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-ribose(out) + H2O = ADP + D-ribose(in) + H(+) +
CC phosphate; Xref=Rhea:RHEA:29903, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:47013, ChEBI:CHEBI:456216; EC=7.5.2.7;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01716};
CC -!- SUBUNIT: The complex is composed of an ATP-binding protein (RbsA), two
CC transmembrane proteins (RbsC) and a solute-binding protein (RbsB).
CC {ECO:0000255|HAMAP-Rule:MF_01716}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01716};
CC Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01716}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Ribose importer
CC (TC 3.A.1.2.1) family. {ECO:0000255|HAMAP-Rule:MF_01716}.
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DR EMBL; AL939113; CAB66285.1; -; Genomic_DNA.
DR RefSeq; NP_626977.1; NC_003888.3.
DR RefSeq; WP_011028557.1; NZ_VNID01000020.1.
DR AlphaFoldDB; Q9RDI1; -.
DR SMR; Q9RDI1; -.
DR STRING; 100226.SCO2746; -.
DR GeneID; 1098180; -.
DR KEGG; sco:SCO2746; -.
DR PATRIC; fig|100226.15.peg.2802; -.
DR eggNOG; COG1129; Bacteria.
DR HOGENOM; CLU_000604_92_3_11; -.
DR InParanoid; Q9RDI1; -.
DR OMA; IKMLSGA; -.
DR PhylomeDB; Q9RDI1; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015611; F:ABC-type D-ribose transporter activity; IEA:RHEA.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS51254; RBSA; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW Reference proteome; Repeat; Sugar transport; Translocase; Transport.
FT CHAIN 1..517
FT /note="Ribose import ATP-binding protein RbsA 2"
FT /id="PRO_0000261111"
FT DOMAIN 10..245
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01716"
FT DOMAIN 255..498
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01716"
FT REGION 497..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 42..49
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01716"
SQ SEQUENCE 517 AA; 55117 MW; C57B135E8143A86C CRC64;
MSSRSPDELL RIEGIRKTFP GVVALDSVDF DLRRGEVHVL LGENGAGKST LIKMLSGAYT
PDAGRILAGG EEVRIHGAQD SERLGIATIY QEFNLVPDLT VAENIFLGRQ PRRLGMIDRK
RMDADAEVLL KRVGVNVSPR ARVRELGIAR LQMVEIAKAL SLDARVLIMD EPTAVLTSEE
VDKLFAIVRR LREDGVGIVF ITHHLEEIAA LGDRVTVIRD GRSVGQVPAS TPEDELVRLM
VGRSIEQQYP RERTDAGEAL LKVEGLTRDG VFHDVGFEVR AGEVVGIAGL VGAGRTEVVR
AVFGADPYDA GTVHVAGAPL RRHDVNAAMA AGIGLVPEDR KGQGLVLDAS VEENLGLVTL
RSTARAGLVD LKGQHTAAER IAGQLGVRMA GLGQHVRTLS GGNQQKVVIG KWLLANTKVL
ILDEPTRGID VGAKVEIYQL INELTAAGAA VLMISSDLPE VLGMSDRVVV MAQGRVAGEL
TAEQATQDAV MALAVSTHTG NSPHSGGTDG TEASRGH
