ID   RBSA_LACLA              Reviewed;         492 AA.
AC   Q9CF44;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Ribose import ATP-binding protein RbsA {ECO:0000255|HAMAP-Rule:MF_01716};
DE            EC=7.5.2.7 {ECO:0000255|HAMAP-Rule:MF_01716};
GN   Name=rbsA {ECO:0000255|HAMAP-Rule:MF_01716}; OrderedLocusNames=LL1637;
GN   ORFNames=L84240;
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403;
RX   PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- FUNCTION: Part of the ABC transporter complex RbsABC involved in ribose
CC       import. Responsible for energy coupling to the transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_01716}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-ribose(out) + H2O = ADP + D-ribose(in) + H(+) +
CC         phosphate; Xref=Rhea:RHEA:29903, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:47013, ChEBI:CHEBI:456216; EC=7.5.2.7;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01716};
CC   -!- SUBUNIT: The complex is composed of an ATP-binding protein (RbsA), two
CC       transmembrane proteins (RbsC) and a solute-binding protein (RbsB).
CC       {ECO:0000255|HAMAP-Rule:MF_01716}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01716};
CC       Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01716}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Ribose importer
CC       (TC 3.A.1.2.1) family. {ECO:0000255|HAMAP-Rule:MF_01716}.
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DR   EMBL; AE005176; AAK05735.1; -; Genomic_DNA.
DR   PIR; E86829; E86829.
DR   RefSeq; NP_267793.1; NC_002662.1.
DR   RefSeq; WP_010906071.1; NC_002662.1.
DR   AlphaFoldDB; Q9CF44; -.
DR   SMR; Q9CF44; -.
DR   STRING; 272623.L84240; -.
DR   PaxDb; Q9CF44; -.
DR   PRIDE; Q9CF44; -.
DR   EnsemblBacteria; AAK05735; AAK05735; L84240.
DR   KEGG; lla:L84240; -.
DR   PATRIC; fig|272623.7.peg.1759; -.
DR   eggNOG; COG1129; Bacteria.
DR   HOGENOM; CLU_000604_92_3_9; -.
DR   OMA; AKREIYQ; -.
DR   Proteomes; UP000002196; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015611; F:ABC-type D-ribose transporter activity; IEA:RHEA.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR   PROSITE; PS51254; RBSA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Reference proteome; Repeat; Sugar transport; Translocase; Transport.
FT   CHAIN           1..492
FT                   /note="Ribose import ATP-binding protein RbsA"
FT                   /id="PRO_0000261072"
FT   DOMAIN          3..239
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01716"
FT   DOMAIN          249..492
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01716"
FT   BINDING         35..42
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01716"
SQ   SEQUENCE   492 AA;  54251 MW;  D18E91E7BF5857A2 CRC64;
     MKIEMKNISK SFGTNKVLEA IDLTINSGEV HALMGENGAG KSTLMNILTG LFPASGGEIE
     IDSEKKIFKN PQEAEGFGIS FIHQEMNTWP DLTVLENLFL GREIKNKFGI LDTKAMRKKA
     NFAFEQLGVK IDLDKEIGNL SVGQQQMVEI AKSFLSDLKI LIMDEPTAAL TERETERLFS
     VIAGLKNQGV GIIYISHRME EIFKITDCIT VMRDGLVIDT QKTKETNVDE LVRKMVGRSI
     TDYYPPKNAE IREIVFEADH LSAEFFKDIS FSVRSGEILG FAGLMGAGRT EVMRAIFGID
     KLKSGTIKIN GKSLTINNPA QAIKEGIGFL TEDRKDEGLV LDFSIKDNIT LPSTKDFIHH
     GLFDDKTATT FVKQLSERLN VKATDEEQIV GSLSGGNQQK VVLAKWIGIA PKVLILDEPT
     RGVDVGAKRE IYQLMNELAE RGVPIIMISS DLPEILGVAD RIAVMHEGEI AGILAKNEAT
     QENVMQLATG GQ