RBSD_SALTY
ID RBSD_SALTY Reviewed; 139 AA.
AC Q8ZKW0;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=D-ribose pyranase {ECO:0000255|HAMAP-Rule:MF_01661};
DE EC=5.4.99.62 {ECO:0000255|HAMAP-Rule:MF_01661};
GN Name=rbsD {ECO:0000255|HAMAP-Rule:MF_01661}; OrderedLocusNames=STM3881;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Catalyzes the interconversion of beta-pyran and beta-furan
CC forms of D-ribose. {ECO:0000255|HAMAP-Rule:MF_01661}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=beta-D-ribopyranose = beta-D-ribofuranose;
CC Xref=Rhea:RHEA:25432, ChEBI:CHEBI:27476, ChEBI:CHEBI:47002;
CC EC=5.4.99.62; Evidence={ECO:0000255|HAMAP-Rule:MF_01661};
CC -!- PATHWAY: Carbohydrate metabolism; D-ribose degradation; D-ribose 5-
CC phosphate from beta-D-ribopyranose: step 1/2. {ECO:0000255|HAMAP-
CC Rule:MF_01661}.
CC -!- SUBUNIT: Homodecamer. {ECO:0000255|HAMAP-Rule:MF_01661}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01661}.
CC -!- SIMILARITY: Belongs to the RbsD / FucU family. RbsD subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01661}.
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DR EMBL; AE006468; AAL22739.1; -; Genomic_DNA.
DR RefSeq; NP_462780.1; NC_003197.2.
DR RefSeq; WP_000715944.1; NC_003197.2.
DR PDB; 3E7N; X-ray; 2.45 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O=1-139.
DR PDBsum; 3E7N; -.
DR AlphaFoldDB; Q8ZKW0; -.
DR SMR; Q8ZKW0; -.
DR STRING; 99287.STM3881; -.
DR PaxDb; Q8ZKW0; -.
DR EnsemblBacteria; AAL22739; AAL22739; STM3881.
DR GeneID; 1255408; -.
DR KEGG; stm:STM3881; -.
DR PATRIC; fig|99287.12.peg.4111; -.
DR HOGENOM; CLU_135498_0_0_6; -.
DR OMA; IIRTGEC; -.
DR PhylomeDB; Q8ZKW0; -.
DR BioCyc; SENT99287:STM3881-MON; -.
DR UniPathway; UPA00916; UER00888.
DR EvolutionaryTrace; Q8ZKW0; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0062193; F:D-ribose pyranase activity; IEA:UniProtKB-EC.
DR GO; GO:0016872; F:intramolecular lyase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016866; F:intramolecular transferase activity; IBA:GO_Central.
DR GO; GO:0048029; F:monosaccharide binding; IEA:InterPro.
DR GO; GO:0019303; P:D-ribose catabolic process; IBA:GO_Central.
DR Gene3D; 3.40.1650.10; -; 1.
DR HAMAP; MF_01661; D_rib_pyranase; 1.
DR InterPro; IPR023064; D-ribose_pyranase.
DR InterPro; IPR023750; RbsD-like_sf.
DR InterPro; IPR007721; RbsD_FucU.
DR PANTHER; PTHR37831; PTHR37831; 1.
DR Pfam; PF05025; RbsD_FucU; 1.
DR SUPFAM; SSF102546; SSF102546; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Carbohydrate metabolism; Cytoplasm; Isomerase;
KW Reference proteome.
FT CHAIN 1..139
FT /note="D-ribose pyranase"
FT /id="PRO_0000346253"
FT ACT_SITE 20
FT /note="Proton donor"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01661"
FT BINDING 28
FT /ligand="substrate"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01661"
FT BINDING 106
FT /ligand="substrate"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01661"
FT BINDING 128..130
FT /ligand="substrate"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01661"
FT STRAND 1..5
FT /evidence="ECO:0007829|PDB:3E7N"
FT HELIX 9..17
FT /evidence="ECO:0007829|PDB:3E7N"
FT STRAND 23..27
FT /evidence="ECO:0007829|PDB:3E7N"
FT STRAND 37..41
FT /evidence="ECO:0007829|PDB:3E7N"
FT HELIX 51..61
FT /evidence="ECO:0007829|PDB:3E7N"
FT STRAND 64..70
FT /evidence="ECO:0007829|PDB:3E7N"
FT HELIX 73..76
FT /evidence="ECO:0007829|PDB:3E7N"
FT HELIX 78..95
FT /evidence="ECO:0007829|PDB:3E7N"
FT STRAND 100..104
FT /evidence="ECO:0007829|PDB:3E7N"
FT HELIX 106..113
FT /evidence="ECO:0007829|PDB:3E7N"
FT STRAND 116..121
FT /evidence="ECO:0007829|PDB:3E7N"
FT STRAND 131..135
FT /evidence="ECO:0007829|PDB:3E7N"
SQ SEQUENCE 139 AA; 15189 MW; 879C16F6C2A1DE62 CRC64;
MKKGTVLNSE ISSVISRLGH TDTLVVCDAG LPIPNSTARI DMALTQGVPS FMQVVDVVTR
EMQVEAAILA TEIKQQNPQL HETLLTHLEQ LQQHQGNTIK ISYTTHEQFK KLTADSQAVI
RSGECSPYAN VILCAGVTF
