ID   RBSR_ALKHC              Reviewed;         331 AA.
AC   Q9K6K2;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 117.
DE   RecName: Full=Ribose operon repressor;
GN   Name=rbsR; OrderedLocusNames=BH3727;
OS   Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS   / JCM 9153 / C-125) (Bacillus halodurans).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX   NCBI_TaxID=272558;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX   PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA   Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA   Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT   "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT   and genomic sequence comparison with Bacillus subtilis.";
RL   Nucleic Acids Res. 28:4317-4331(2000).
CC   -!- FUNCTION: Transcriptional repressor for the ribose rbsDACBK operon.
CC       {ECO:0000250}.
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DR   EMBL; BA000004; BAB07446.1; -; Genomic_DNA.
DR   PIR; G84115; G84115.
DR   RefSeq; WP_010899852.1; NC_002570.2.
DR   AlphaFoldDB; Q9K6K2; -.
DR   SMR; Q9K6K2; -.
DR   STRING; 272558.10176351; -.
DR   EnsemblBacteria; BAB07446; BAB07446; BAB07446.
DR   KEGG; bha:BH3727; -.
DR   eggNOG; COG1609; Bacteria.
DR   HOGENOM; CLU_037628_6_1_9; -.
DR   OMA; FAGNDMI; -.
DR   OrthoDB; 1796334at2; -.
DR   Proteomes; UP000001258; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd01392; HTH_LacI; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR000843; HTH_LacI.
DR   InterPro; IPR046335; LacI/GalR-like_sensor.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   Pfam; PF00356; LacI; 1.
DR   Pfam; PF13377; Peripla_BP_3; 1.
DR   PRINTS; PR00036; HTHLACI.
DR   SMART; SM00354; HTH_LACI; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
DR   PROSITE; PS00356; HTH_LACI_1; 1.
DR   PROSITE; PS50932; HTH_LACI_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..331
FT                   /note="Ribose operon repressor"
FT                   /id="PRO_0000107983"
FT   DOMAIN          1..56
FT                   /note="HTH lacI-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
FT   DNA_BIND        4..23
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
SQ   SEQUENCE   331 AA;  36637 MW;  DF228BD875BF607F CRC64;
     MTTIRDVAKH AKVSVATVSR VLNKKGYVSK EAEEAVLQAI KELNYQPSSV ARSLYHKTSG
     MIGLLIPDIS NPFFPELARA VEDVASTYGY TVVLCNTDEE IEKERKYLQA LKQKYVDGVI
     LTTSFLPYKE YEQLNIPMVA LDRYVNENIP LVASQNKAGA RLATEHLLEQ GCQFIAHIRG
     PKGVTPAEDR YEGFKEVVEE QEVANIVVSA DFHIDEAQKV TRALLETHPT IDGIFASSDV
     VAAGAMKAAH MMGKRIPDDL QIVGFDGIPL GNMLVPSLTT VEQPIYDLGA VSTRLLIKQI
     EKKPLDTYRY EIPTKLVVRE TTKGGENSEN A