RBSR_HAEIN
ID RBSR_HAEIN Reviewed; 332 AA.
AC P44329;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Ribose operon repressor;
GN Name=rbsR; OrderedLocusNames=HI_0506;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- FUNCTION: Transcriptional repressor for the ribose rbsDACBK operon.
CC {ECO:0000250}.
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DR EMBL; L42023; AAC22164.1; -; Genomic_DNA.
DR PIR; C64073; C64073.
DR RefSeq; NP_438664.1; NC_000907.1.
DR RefSeq; WP_005693667.1; NC_000907.1.
DR AlphaFoldDB; P44329; -.
DR SMR; P44329; -.
DR STRING; 71421.HI_0506; -.
DR EnsemblBacteria; AAC22164; AAC22164; HI_0506.
DR KEGG; hin:HI_0506; -.
DR PATRIC; fig|71421.8.peg.525; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_2_6; -.
DR OMA; IMQRYPS; -.
DR PhylomeDB; P44329; -.
DR BioCyc; HINF71421:G1GJ1-519-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd01392; HTH_LacI; 1.
DR Gene3D; 1.10.260.40; -; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; SSF47413; 1.
DR SUPFAM; SSF53822; SSF53822; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..332
FT /note="Ribose operon repressor"
FT /id="PRO_0000107989"
FT DOMAIN 2..56
FT /note="HTH lacI-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
FT DNA_BIND 4..23
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
SQ SEQUENCE 332 AA; 36715 MW; E335C70E6030953F CRC64;
MATMKDIARL AQVSTSTVSH VINGSRFVSD EIREKVMRIV AELNYTPSAV ARSLKVRETK
TIGLLVTATN NPFFAEVMAG VEQYCQKNQY NLIIATTGGD AKRLQQNLQT LMHKQVDGLL
LMCGDSRFQA DIELAISLPL VVMDWWFTEL NADKILENSA LGGYLATKAL IDAGHRKIGI
ITGNLKKSVA QNRLQGYKNA LSEAKIALNP HWIVESHFDF EGGVLGIQSL LTQSSRPTAV
FCCSDTIAVG AYQAIQQQGL RIPQDLSIMG YDDIELARYL SPPLSTICQP KAELGKLAVE
TLLQRIKNPN ENYRTLVLEP TCVLRESIYS LK
