ID   RBSR_LACLA              Reviewed;         327 AA.
AC   Q9CF41;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=Ribose operon repressor;
GN   Name=rbsR; OrderedLocusNames=LL1640; ORFNames=L0145;
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403;
RX   PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- FUNCTION: Transcriptional repressor for the ribose rbsDACBK operon.
CC       {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE005176; AAK05738.1; -; Genomic_DNA.
DR   PIR; H86829; H86829.
DR   RefSeq; NP_267796.1; NC_002662.1.
DR   RefSeq; WP_010906073.1; NC_002662.1.
DR   AlphaFoldDB; Q9CF41; -.
DR   SMR; Q9CF41; -.
DR   STRING; 272623.L0145; -.
DR   PaxDb; Q9CF41; -.
DR   EnsemblBacteria; AAK05738; AAK05738; L0145.
DR   KEGG; lla:L0145; -.
DR   PATRIC; fig|272623.7.peg.1762; -.
DR   eggNOG; COG1609; Bacteria.
DR   HOGENOM; CLU_037628_6_1_9; -.
DR   OMA; MVFVDRW; -.
DR   Proteomes; UP000002196; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd01392; HTH_LacI; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR000843; HTH_LacI.
DR   InterPro; IPR046335; LacI/GalR-like_sensor.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   Pfam; PF00356; LacI; 1.
DR   Pfam; PF13377; Peripla_BP_3; 1.
DR   SMART; SM00354; HTH_LACI; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
DR   PROSITE; PS50932; HTH_LACI_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..327
FT                   /note="Ribose operon repressor"
FT                   /id="PRO_0000107990"
FT   DOMAIN          1..56
FT                   /note="HTH lacI-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
FT   DNA_BIND        4..23
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
SQ   SEQUENCE   327 AA;  36775 MW;  4014302D325B48A0 CRC64;
     MTTIKQVALE AGVSKSTVSR FIAQNGYVSD EAREKIERAI KKLNFRPNLS AQSLKTKKNQ
     LVGLLLPDIS NPFFPMLAKG AEEFLKEKGY RVMLGNIGEK NQSEQDYLKV LIQSNAAGII
     STHDFKEDFP DLDIPTVIVD RVGHKSNYGV FSDNESGGRL AAKVIVTAGA KKVAVVSGPL
     NATNINNRFK SSIAYLKEKQ VDFKAFYSQS YDFEEIQKEA REVLANEENF DSIIAPSDIH
     AMAYIHEIHR LNKKIPEDIQ IIGYDDIQMS QFIYPALSTI HQSAYQMGLE AAQLIYKIAT
     DQAIEKSKIE LPVHYVARET IRQKRKE