ID   RBSU_LACJO              Reviewed;         296 AA.
AC   P60949;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   13-APR-2004, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Putative ribose uptake protein RbsU;
GN   Name=rbsU; OrderedLocusNames=LJ_1213;
OS   Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=257314;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CNCM I-1225 / La1 / NCC 533;
RX   PubMed=14983040; DOI=10.1073/pnas.0307327101;
RA   Pridmore R.D., Berger B., Desiere F., Vilanova D., Barretto C.,
RA   Pittet A.-C., Zwahlen M.-C., Rouvet M., Altermann E., Barrangou R.,
RA   Mollet B., Mercenier A., Klaenhammer T., Arigoni F., Schell M.A.;
RT   "The genome sequence of the probiotic intestinal bacterium Lactobacillus
RT   johnsonii NCC 533.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:2512-2517(2004).
CC   -!- FUNCTION: Could be involved in the uptake of ribose. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GRP transporter (TC 2.A.7.5) family.
CC       {ECO:0000305}.
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DR   EMBL; AE017198; AAS09034.1; -; Genomic_DNA.
DR   RefSeq; WP_011162042.1; NC_005362.1.
DR   AlphaFoldDB; P60949; -.
DR   SMR; P60949; -.
DR   STRING; 257314.LJ_1213; -.
DR   EnsemblBacteria; AAS09034; AAS09034; LJ_1213.
DR   KEGG; ljo:LJ_1213; -.
DR   eggNOG; COG4975; Bacteria.
DR   HOGENOM; CLU_076024_0_1_9; -.
DR   OMA; GWACAQI; -.
DR   Proteomes; UP000000581; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR010651; Sugar_transport.
DR   PANTHER; PTHR16119; PTHR16119; 2.
DR   Pfam; PF06800; Sugar_transport; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..296
FT                   /note="Putative ribose uptake protein RbsU"
FT                   /id="PRO_0000213634"
FT   TRANSMEM        2..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        182..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        221..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        245..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        276..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   296 AA;  31421 MW;  CDA30D3B2A96926D CRC64;
     MNGIALLIGL GPLLGWGLFP TIASKIGGKP VNQIIGTTFG TFIFALVYNL VQGIALPSGA
     ALIWSIISGI GWASAQILTF HSFTLVGSSR AMPITTAFQL LGTSLWGVFA LGDWPSTSDK
     LVGFLALALI ILGAWMTTWS EHKTDENSAK LRKAVIILLV GEIGYWAYSA APQAAKIDGS
     KAFLPQAIGM CLVAICYAVY LKVKEPSQRS ALAQGVSYKQ IISGFFFAFA ALTYLISAQP
     NMNGLATGFI LSQTSVVLAT LTGIWFLHEK KTKKEMVVTL IGLAIIIGAA TMTVIV