ID   RBSU_STAAR              Reviewed;         293 AA.
AC   Q6GK41;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Putative ribose uptake protein RbsU;
GN   Name=rbsU; OrderedLocusNames=SAR0268;
OS   Staphylococcus aureus (strain MRSA252).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282458;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MRSA252;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- FUNCTION: Could be involved in the uptake of ribose. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GRP transporter (TC 2.A.7.5) family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BX571856; CAG39294.1; -; Genomic_DNA.
DR   RefSeq; WP_000029204.1; NC_002952.2.
DR   AlphaFoldDB; Q6GK41; -.
DR   KEGG; sar:SAR0268; -.
DR   HOGENOM; CLU_076024_0_1_9; -.
DR   OMA; GWACAQI; -.
DR   OrthoDB; 778970at2; -.
DR   Proteomes; UP000000596; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR010651; Sugar_transport.
DR   PANTHER; PTHR16119; PTHR16119; 2.
DR   Pfam; PF06800; Sugar_transport; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Sugar transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..293
FT                   /note="Putative ribose uptake protein RbsU"
FT                   /id="PRO_0000213640"
FT   TRANSMEM        5..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        212..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        241..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        273..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   293 AA;  31243 MW;  86CCFED7D4404039 CRC64;
     MSIVALLIGL GPLIGWGFFP TVASKFGGKP VHQIIGATVG TLIFAIILAV VTSSGFPTGT
     NLLFALLSGA GWGFGQIITF KAFELVGSSR AMPVTTAFQL LGASLWGVFA LGNWPGIGHK
     IIGFTALVVI LIGARMTVWS ERKEASNAKN LRRAVVLLLI GEFGYWLYSA APQATSIDGL
     TAFLPQAMGM VIVAVIYGFM NMKAENPFRN KITWLQIISG FFFAFGALTY LISAQPNMNG
     LATGFILSQT SVVLATLTGI YFLKQHKTSK EMVITIIGLV LILVAASVTV FIK