ID   RBTN1_BOVIN             Reviewed;         156 AA.
AC   Q0P5B3;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Rhombotin-1;
DE   AltName: Full=LIM domain only protein 1;
DE            Short=LMO-1;
GN   Name=LMO1; Synonyms=RBTN1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal cerebellum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in gene regulation within neural lineage
CC       cells potentially by direct DNA binding or by binding to other
CC       transcription factors.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- TISSUE SPECIFICITY: Expressed in the brain and not in the thymus.
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DR   EMBL; BC120273; AAI20274.1; -; mRNA.
DR   RefSeq; NP_001069363.1; NM_001075895.2.
DR   RefSeq; XP_005216032.1; XM_005215975.2.
DR   AlphaFoldDB; Q0P5B3; -.
DR   SMR; Q0P5B3; -.
DR   STRING; 9913.ENSBTAP00000042937; -.
DR   PaxDb; Q0P5B3; -.
DR   Ensembl; ENSBTAT00000075089; ENSBTAP00000057677; ENSBTAG00000016320.
DR   GeneID; 527152; -.
DR   KEGG; bta:527152; -.
DR   CTD; 4004; -.
DR   VEuPathDB; HostDB:ENSBTAG00000016320; -.
DR   VGNC; VGNC:30933; LMO1.
DR   eggNOG; KOG0490; Eukaryota.
DR   GeneTree; ENSGT00940000153908; -.
DR   HOGENOM; CLU_001357_7_1_1; -.
DR   InParanoid; Q0P5B3; -.
DR   OMA; CPRTGRP; -.
DR   OrthoDB; 1307952at2759; -.
DR   TreeFam; TF351071; -.
DR   Proteomes; UP000009136; Chromosome 15.
DR   Bgee; ENSBTAG00000016320; Expressed in oocyte and 90 other tissues.
DR   ExpressionAtlas; Q0P5B3; baseline.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0140297; F:DNA-binding transcription factor binding; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR001781; Znf_LIM.
DR   Pfam; PF00412; LIM; 2.
DR   SMART; SM00132; LIM; 2.
DR   PROSITE; PS00478; LIM_DOMAIN_1; 2.
DR   PROSITE; PS50023; LIM_DOMAIN_2; 2.
PE   2: Evidence at transcript level;
KW   LIM domain; Metal-binding; Nucleus; Reference proteome; Repeat; Zinc.
FT   CHAIN           1..156
FT                   /note="Rhombotin-1"
FT                   /id="PRO_0000269568"
FT   DOMAIN          22..84
FT                   /note="LIM zinc-binding 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00125"
FT   DOMAIN          86..148
FT                   /note="LIM zinc-binding 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00125"
SQ   SEQUENCE   156 AA;  17823 MW;  81AFA2E88B0A11C1 CRC64;
     MMVLDKEDGV PMLSVQPKGK QKGCAGCNRK IKDRYLLKAL DQYWHEDCLK CACCDCRLGE
     VGSTLYTKAN LILCRRDYLR LFGTTGNCAA CSKLIPAFEM VMRARDNVYH LDCFACQLCN
     QRFCVGDKFF LKNNMILCQM DYEEGQLNGT FDSHVQ