RBTN1_XENLA
ID RBTN1_XENLA Reviewed; 156 AA.
AC Q3B8H4;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 61.
DE RecName: Full=Rhombotin-1;
DE AltName: Full=LIM domain only protein 1;
DE Short=LMO-1;
GN Name=lmo1 {ECO:0000250|UniProtKB:P25800};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1] {ECO:0000312|EMBL:AAI06432.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Neurula {ECO:0000312|EMBL:AAI06432.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in gene regulation within neural lineage
CC cells potentially by direct DNA binding or by binding to other
CC transcription factors. {ECO:0000250|UniProtKB:Q924W9}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q924W9}.
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DR EMBL; BC106431; AAI06432.1; -; mRNA.
DR RefSeq; NP_001089735.1; NM_001096266.1.
DR AlphaFoldDB; Q3B8H4; -.
DR SMR; Q3B8H4; -.
DR DNASU; 734798; -.
DR GeneID; 734798; -.
DR KEGG; xla:734798; -.
DR CTD; 734798; -.
DR Xenbase; XB-GENE-17346296; lmo1.S.
DR OMA; CPRTGRP; -.
DR OrthoDB; 1307952at2759; -.
DR Proteomes; UP000186698; Chromosome 4S.
DR Bgee; 734798; Expressed in brain and 14 other tissues.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR001781; Znf_LIM.
DR Pfam; PF00412; LIM; 2.
DR SMART; SM00132; LIM; 2.
DR PROSITE; PS00478; LIM_DOMAIN_1; 2.
DR PROSITE; PS50023; LIM_DOMAIN_2; 2.
PE 2: Evidence at transcript level;
KW LIM domain; Metal-binding; Nucleus; Reference proteome; Repeat; Zinc.
FT CHAIN 1..156
FT /note="Rhombotin-1"
FT /id="PRO_0000318110"
FT DOMAIN 22..84
FT /note="LIM zinc-binding 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00125"
FT DOMAIN 86..148
FT /note="LIM zinc-binding 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00125"
SQ SEQUENCE 156 AA; 17814 MW; D0A51E0E86BDDEAD CRC64;
MMVLEKEDGV PMLSVQPKGK QKGCAGCNRK IKDRYLLKAL DKYWHEDCLK CACCDCRLGE
VGSTLYTKAN LILCRRDYLR LFGTTGNCAA CSKLIPAFEM VMRARDNVYH LDCFACQLCN
QRFCVGDKFF LKNNMILCQM DYEEGQLNGS FDSQVQ