ID   RCAC_MICDP              Reviewed;         651 AA.
AC   Q01473;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   13-APR-2004, sequence version 2.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Protein RcaC;
GN   Name=rcaC;
OS   Microchaete diplosiphon (Fremyella diplosiphon).
OC   Bacteria; Cyanobacteria; Nostocales; Rivulariaceae; Microchaete.
OX   NCBI_TaxID=1197;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=FD33;
RX   PubMed=1409650; DOI=10.1073/pnas.89.20.9415;
RA   Chiang G.G., Schaefer M.R., Grossman A.R.;
RT   "Complementation of a red-light-indifferent cyanobacterial mutant.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:9415-9419(1992).
CC   -!- FUNCTION: Required for chromatic adaptation. Thought to be a positive
CC       regulator of phycobiliproteins.
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DR   EMBL; M95680; AAA24892.1; -; Genomic_DNA.
DR   PIR; A47210; A47210.
DR   PIR; S27576; S27576.
DR   AlphaFoldDB; Q01473; -.
DR   SMR; Q01473; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00383; trans_reg_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR036641; HPT_dom_sf.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR039420; WalR-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR48111; PTHR48111; 2.
DR   Pfam; PF01627; Hpt; 1.
DR   Pfam; PF00072; Response_reg; 2.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   SMART; SM00448; REC; 3.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF47226; SSF47226; 1.
DR   SUPFAM; SSF52172; SSF52172; 3.
DR   PROSITE; PS51755; OMPR_PHOB; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 3.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Phosphoprotein; Repeat; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..651
FT                   /note="Protein RcaC"
FT                   /id="PRO_0000081207"
FT   DOMAIN          2..116
FT                   /note="Response regulatory 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DOMAIN          384..519
FT                   /note="Response regulatory 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DOMAIN          527..643
FT                   /note="Response regulatory 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DNA_BIND        124..223
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01091"
FT   MOD_RES         51
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   651 AA;  73278 MW;  9A8CDDCF808F4F70 CRC64;
     MKILLVEDDD VLIKVLTKNL TTHHYIVDVV KDGEMGWTYG STFEYDLIIL DIMLPNLDGI
     SLCKRFRAQG YTVPILLLTA QDNITAKVQG LDAGADDYVV KPFDPIELIA RIRALLRRGS
     NNPFPLLTWG DLLLNPSTCE VTYNGCPLNL TTMEYDLLEL LLRNCQHVFS SEELLDKLWS
     SEDFPSEATV RSHVRRLRHK LVAAGAPHDF IATMHGRGYY LKAPSTEEVN NLSVTPENNS
     HSAAVIVKSR ETESDRPQHL IPSDSQQQYL AFLNETWTRT KPQSLDQMGI LLQIVRDLQT
     NQLTPQQQTQ AQHVAHKLAG TLGIFGLTKT MHIARQLEYW LGGRERLQPK HAPLMKTLVT
     ALQQDIDHTT LIQLSQIPAG QSPLLLMISA DNEFNQSIVA VAASRGIRIQ IAPTPDIAPA
     MLTNEPVLDG FGEDPDVILM RLPSMPSRAE VIEQPNSELS NIWKTLQTFA ERYPKLPIVV
     IGDRGEMSDR LEAMRRGGKL FLVTPTPPEQ IVDTVVNLLR DPEIPNKVMI LDDDQDWLRT
     LPTLLKPWGF KVTTLADPQQ FWTVLQAVTP DALVLDVNMP QINGFELCQL LRSDPHWQRL
     PVLFLSVLTD PTTQNQAFAV GGDDYLCKPV KGVELANRIL RRLQRVRAWA N