RCAN3_CHICK
ID RCAN3_CHICK Reviewed; 249 AA.
AC Q5ZJV6;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 2.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Calcipressin-3;
DE AltName: Full=Regulator of calcineurin 3;
GN Name=RCAN3; ORFNames=RCJMB04_15g5;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: Inhibits calcineurin-dependent transcriptional responses by
CC binding to the catalytic domain of calcineurin A. Could play a role
CC during central nervous system development (By similarity).
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RCAN family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAG31987.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AJ720328; CAG31987.1; ALT_INIT; mRNA.
DR RefSeq; NP_001026078.1; NM_001030907.1.
DR RefSeq; XP_015153166.1; XM_015297680.1.
DR AlphaFoldDB; Q5ZJV6; -.
DR SMR; Q5ZJV6; -.
DR STRING; 9031.ENSGALP00000006796; -.
DR PaxDb; Q5ZJV6; -.
DR Ensembl; ENSGALT00000006807; ENSGALP00000006796; ENSGALG00000004282.
DR GeneID; 419698; -.
DR KEGG; gga:419698; -.
DR CTD; 11123; -.
DR VEuPathDB; HostDB:geneid_419698; -.
DR eggNOG; KOG4019; Eukaryota.
DR GeneTree; ENSGT00940000159501; -.
DR HOGENOM; CLU_076190_0_0_1; -.
DR InParanoid; Q5ZJV6; -.
DR OMA; RMRVNYN; -.
DR OrthoDB; 1585262at2759; -.
DR PhylomeDB; Q5ZJV6; -.
DR TreeFam; TF313579; -.
DR PRO; PR:Q5ZJV6; -.
DR Proteomes; UP000000539; Chromosome 23.
DR Bgee; ENSGALG00000004282; Expressed in cerebellum and 13 other tissues.
DR ExpressionAtlas; Q5ZJV6; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0008597; F:calcium-dependent protein serine/threonine phosphatase regulator activity; IBA:GO_Central.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0019722; P:calcium-mediated signaling; IBA:GO_Central.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR006931; Calcipressin.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034923; RCAN3.
DR PANTHER; PTHR10300; PTHR10300; 1.
DR PANTHER; PTHR10300:SF6; PTHR10300:SF6; 1.
DR Pfam; PF04847; Calcipressin; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..249
FT /note="Calcipressin-3"
FT /id="PRO_0000295273"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..219
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 249 AA; 28301 MW; 8455C500C961A561 CRC64;
MLRDTMKSWS DSQSDLYSSD QEEEEQMIFG ENEDDFEEMM DLSDLPTSLF ACSVHEAVFE
VQEEKERFEA LFTVYDNQVT FQLFKSFRRV RINFSNPEAA ARARIELHET DFSGKKLKLY
FAQVQVSSEV GDKSYLLPPQ PVKQFLISPP ASPPVGWKQS EDATPLINYD LLCAVSKLGP
GEKYELHAGT ESTPSVVVHV CESETEEEEE IKNPKQKIMQ TRRPEPPATI LNESKAFDCT
LEVGGTIHC
