RCA_NOSS1
ID RCA_NOSS1 Reviewed; 414 AA.
AC P58555;
DT 23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2002, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Ribulose bisphosphate carboxylase/oxygenase activase;
DE Short=RA;
DE Short=RuBisCO activase;
GN Name=rca; OrderedLocusNames=alr1533;
OS Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=103690;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT "Complete genomic sequence of the filamentous nitrogen-fixing
RT cyanobacterium Anabaena sp. strain PCC 7120.";
RL DNA Res. 8:205-213(2001).
CC -!- FUNCTION: Activation of RuBisCO (ribulose-1,5-bisohosphate
CC carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent
CC carboxylation of the epsilon-amino group of lysine leading to a
CC carbamate structure. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RuBisCO activase family. {ECO:0000305}.
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DR EMBL; BA000019; BAB77899.1; -; Genomic_DNA.
DR PIR; AG1997; AG1997.
DR RefSeq; WP_010995702.1; NZ_RSCN01000022.1.
DR PDB; 6HAS; X-ray; 1.38 A; A/B=325-414.
DR PDB; 6Z1D; X-ray; 2.71 A; A/B=2-291.
DR PDB; 6Z1E; X-ray; 2.45 A; A/B=2-291.
DR PDB; 6Z1F; EM; 2.86 A; 1/2/3/4/5/6=2-291.
DR PDB; 6Z1G; EM; 8.20 A; A=325-414.
DR PDBsum; 6HAS; -.
DR PDBsum; 6Z1D; -.
DR PDBsum; 6Z1E; -.
DR PDBsum; 6Z1F; -.
DR PDBsum; 6Z1G; -.
DR AlphaFoldDB; P58555; -.
DR SMR; P58555; -.
DR STRING; 103690.17135353; -.
DR PRIDE; P58555; -.
DR EnsemblBacteria; BAB77899; BAB77899; BAB77899.
DR KEGG; ana:alr1533; -.
DR eggNOG; COG0464; Bacteria.
DR eggNOG; COG4451; Bacteria.
DR OMA; MEKFYWE; -.
DR OrthoDB; 602142at2; -.
DR Proteomes; UP000002483; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.30.190.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR044960; RCA-like.
DR InterPro; IPR000894; RuBisCO_ssu_dom.
DR InterPro; IPR036385; RuBisCO_ssu_sf.
DR PANTHER; PTHR32429; PTHR32429; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00101; RuBisCO_small; 1.
DR SMART; SM00961; RuBisCO_small; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF55239; SSF55239; 1.
PE 1: Evidence at protein level;
KW 3D-structure; ATP-binding; Nucleotide-binding; Reference proteome.
FT CHAIN 1..414
FT /note="Ribulose bisphosphate carboxylase/oxygenase
FT activase"
FT /id="PRO_0000216428"
FT REGION 296..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..326
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 37..44
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
FT HELIX 7..19
FT /evidence="ECO:0007829|PDB:6Z1E"
FT STRAND 31..36
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 43..54
FT /evidence="ECO:0007829|PDB:6Z1E"
FT STRAND 57..62
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 63..67
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 69..71
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 74..92
FT /evidence="ECO:0007829|PDB:6Z1E"
FT STRAND 96..101
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 108..110
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 120..132
FT /evidence="ECO:0007829|PDB:6Z1E"
FT STRAND 140..142
FT /evidence="ECO:0007829|PDB:6Z1F"
FT STRAND 153..158
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 162..164
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 165..169
FT /evidence="ECO:0007829|PDB:6Z1E"
FT STRAND 172..177
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 182..192
FT /evidence="ECO:0007829|PDB:6Z1E"
FT TURN 193..197
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 200..209
FT /evidence="ECO:0007829|PDB:6Z1E"
FT STRAND 210..212
FT /evidence="ECO:0007829|PDB:6Z1F"
FT HELIX 215..223
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 224..226
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 227..237
FT /evidence="ECO:0007829|PDB:6Z1E"
FT TURN 239..241
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 242..247
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 263..274
FT /evidence="ECO:0007829|PDB:6Z1E"
FT HELIX 328..339
FT /evidence="ECO:0007829|PDB:6HAS"
FT STRAND 343..349
FT /evidence="ECO:0007829|PDB:6HAS"
FT HELIX 351..354
FT /evidence="ECO:0007829|PDB:6HAS"
FT TURN 355..357
FT /evidence="ECO:0007829|PDB:6HAS"
FT STRAND 360..367
FT /evidence="ECO:0007829|PDB:6HAS"
FT HELIX 370..383
FT /evidence="ECO:0007829|PDB:6HAS"
FT TURN 384..386
FT /evidence="ECO:0007829|PDB:6HAS"
FT STRAND 387..395
FT /evidence="ECO:0007829|PDB:6HAS"
FT TURN 396..399
FT /evidence="ECO:0007829|PDB:6HAS"
FT STRAND 400..408
FT /evidence="ECO:0007829|PDB:6HAS"
SQ SEQUENCE 414 AA; 46668 MW; E8359F10D8C558DA CRC64;
MSYYIAPRFL DKLAVHITKN FLNIPGVRVP LILGIHGRKG EGKTFQCELA FEKMGIEVTL
ISGGELESPD AGDPARLIRL RYRETAELIK VRGKMCVLMI NDLDAGAGRF DEGTQYTVNT
QLVNATLMNI ADNPTDVQLP GSYDSNPIRR VPIIVTGNDF STLYAPLIRD GRMEKFYWEP
NRDDKVGIVG GIFAEDGLSQ REIEQLVDTF PKQSIDFFSA LRSRIYDIQI RDFIHKVGFE
RISLRVVNSL EAPPEFKKPD FSLAHLIESG NLVLGEQQRV DNSQLVDEYN RLNRGRGYQT
APPPEAPVIQ PVNNSSHKQK TSNTHLSLET QEQIRQILSQ GHKITFEHVD ARRFRTGSWQ
SCGTLHIDAE SDAISTLEAC LVDYDGEYVR MVGIDPKGKR RVVETIIQRP NGKN
