ID   RCC1_CANAX              Reviewed;         464 AA.
AC   P52499;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Protein RCC1;
GN   Name=RCC1;
OS   Candida albicans (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=5476;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CA124;
RA   Nolan T., Rosamond J.;
RL   Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Promotes the exchange of Ran(SPI1)-bound GDP by GTP. Involved
CC       in the control of mitosis. Regulates a variety of nuclear events,
CC       including mitotic check-point, chromosome decondensation and mRNA
CC       processing/transport (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; X96850; CAA65595.1; -; Genomic_DNA.
DR   AlphaFoldDB; P52499; -.
DR   SMR; P52499; -.
DR   VEuPathDB; FungiDB:C7_02780W_A; -.
DR   VEuPathDB; FungiDB:CAWG_05612; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.30; -; 1.
DR   InterPro; IPR009091; RCC1/BLIP-II.
DR   InterPro; IPR000408; Reg_chr_condens.
DR   Pfam; PF00415; RCC1; 3.
DR   PRINTS; PR00633; RCCNDNSATION.
DR   SUPFAM; SSF50985; SSF50985; 1.
DR   PROSITE; PS00625; RCC1_1; 1.
DR   PROSITE; PS00626; RCC1_2; 1.
DR   PROSITE; PS50012; RCC1_3; 5.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Guanine-nucleotide releasing factor; Mitosis;
KW   Nucleus; Repeat.
FT   CHAIN           1..464
FT                   /note="Protein RCC1"
FT                   /id="PRO_0000206635"
FT   REPEAT          23..82
FT                   /note="RCC1 1"
FT   REPEAT          84..135
FT                   /note="RCC1 2"
FT   REPEAT          162..216
FT                   /note="RCC1 3"
FT   REPEAT          269..327
FT                   /note="RCC1 4"
FT   REPEAT          329..390
FT                   /note="RCC1 5"
FT   REPEAT          391..445
FT                   /note="RCC1 6"
FT   REGION          111..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        116..130
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   464 AA;  51286 MW;  168DBDF73C7ED31F CRC64;
     MFVLHSYSKL PNINEYAKAK STPLDVFVWG TGSMCELGLG PSAKNKEVKR PRLNPYLTEE
     KLGGTKIVDF AVGGMHTLAL DGKNRIWSWG GNDSEVLGRD TCQAKEVLKD IDGKNGNDDD
     DDDEDGDLNE AESTPALVEN LPEGEIVQLA ATDNLSAALL SNGDVYSWGC FRCNEGLLGF
     LRDEIKLQKT PLKIKELKKH CPIMRSVKII LLALDSKEWM PGVNGQQYQL GRRILERHRY
     RSLEPQQFGL YNIKYIASGD FHCFAIDHSH NVYAWGLNQY GQCALTGDNG ELEDGSVLMK
     PTLIPELSHK GIKEIAAGEH HTLALTEDGQ VYAWGRYDMK EIGIPKDKLP KSTFKINTGT
     HGSFSFLQNL FAVKIKTIGV GSHHSFAVTE DGVVYAWGFA ETYGPGLGPS IDDVEKPTRI
     VNTATKNEDI LLIGAGGQFS VSGGVKFEDE EKAEVRLDKY EDLE