ID   RCF1_AJECN              Reviewed;         145 AA.
AC   A6RBB3;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=Respiratory supercomplex factor 1, mitochondrial;
GN   Name=RCF1; Synonyms=AIM31; ORFNames=HCAG_06251;
OS   Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma;
OC   unclassified Histoplasma.
OX   NCBI_TaxID=2059318;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAm1 / WU24;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: Cytochrome c oxidase subunit which plays a role in assembly
CC       of respiratory supercomplexes. {ECO:0000250}.
CC   -!- SUBUNIT: Associates with the respiratory chain complex III/complex IV
CC       supercomplex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC       ProRule:PRU00836}.
CC   -!- SIMILARITY: Belongs to the RCF1 family. {ECO:0000305}.
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DR   EMBL; CH476661; EDN10448.1; -; Genomic_DNA.
DR   RefSeq; XP_001538646.1; XM_001538596.1.
DR   AlphaFoldDB; A6RBB3; -.
DR   STRING; 339724.A6RBB3; -.
DR   EnsemblFungi; EDN10448; EDN10448; HCAG_06251.
DR   GeneID; 5444867; -.
DR   KEGG; aje:HCAG_06251; -.
DR   VEuPathDB; FungiDB:HCAG_06251; -.
DR   HOGENOM; CLU_087356_0_2_1; -.
DR   OMA; SVEMNKM; -.
DR   OrthoDB; 1307900at2759; -.
DR   Proteomes; UP000009297; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007667; Hypoxia_induced_domain.
DR   Pfam; PF04588; HIG_1_N; 1.
DR   PROSITE; PS51503; HIG1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..145
FT                   /note="Respiratory supercomplex factor 1, mitochondrial"
FT                   /id="PRO_0000399611"
FT   TRANSMEM        33..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   TRANSMEM        69..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   DOMAIN          6..97
FT                   /note="HIG1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   COILED          86..144
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   145 AA;  17232 MW;  01A165BF597FCA52 CRC64;
     MSNTPLPSSF DAHPEFFQET KWQKFTRRIK EEPLIPIGYA ATSYALWRAY KSMKAGDSIE
     LNRMFRARIY GHAFTLFAIV AGGIYYGQER RQRKEFEKAL QQKQDQEKRD AWLKELEIRD
     KEDKNWRQRH AAIEMAAKEA EKKRG