RCF1_ASHGO
ID RCF1_ASHGO Reviewed; 157 AA.
AC Q756G1;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 86.
DE RecName: Full=Respiratory supercomplex factor 1, mitochondrial;
GN Name=RCF1; Synonyms=AIM31; OrderedLocusNames=AER310W;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Cytochrome c oxidase subunit which plays a role in assembly
CC of respiratory supercomplexes. {ECO:0000250}.
CC -!- SUBUNIT: Associates with the respiratory chain complex III/complex IV
CC supercomplex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC ProRule:PRU00836}.
CC -!- SIMILARITY: Belongs to the RCF1 family. {ECO:0000305}.
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DR EMBL; AE016818; AAS52990.1; -; Genomic_DNA.
DR RefSeq; NP_985166.1; NM_210520.1.
DR AlphaFoldDB; Q756G1; -.
DR SMR; Q756G1; -.
DR STRING; 33169.AAS52990; -.
DR PRIDE; Q756G1; -.
DR EnsemblFungi; AAS52990; AAS52990; AGOS_AER310W.
DR GeneID; 4621379; -.
DR KEGG; ago:AGOS_AER310W; -.
DR eggNOG; KOG4431; Eukaryota.
DR HOGENOM; CLU_087356_1_0_1; -.
DR InParanoid; Q756G1; -.
DR OMA; SVEMNKM; -.
DR Proteomes; UP000000591; Chromosome V.
DR GO; GO:0031305; C:integral component of mitochondrial inner membrane; IEA:EnsemblFungi.
DR GO; GO:0005746; C:mitochondrial respirasome; IEA:EnsemblFungi.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IEA:EnsemblFungi.
DR GO; GO:0097250; P:mitochondrial respirasome assembly; IBA:GO_Central.
DR GO; GO:0010155; P:regulation of proton transport; IEA:EnsemblFungi.
DR InterPro; IPR007667; Hypoxia_induced_domain.
DR Pfam; PF04588; HIG_1_N; 1.
DR PROSITE; PS51503; HIG1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..157
FT /note="Respiratory supercomplex factor 1, mitochondrial"
FT /id="PRO_0000399614"
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT DOMAIN 4..95
FT /note="HIG1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT REGION 120..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 87..157
FT /evidence="ECO:0000255"
SQ SEQUENCE 157 AA; 18367 MW; 259EDEB85B91C844 CRC64;
MSYLPTSSEA DKDLDEMTFS EKMVFHCKRE PLVPAGVLMT TGAILLAIKN VRSGNRRNAQ
KWFRWRVGLQ TGTLVALIAG SFFYGSAKHE QLSKEEQLRQ KAKMREQLWI QELERRDLEV
RRRKQRAEEA RKKAAEMQSE LSGLEQELRE LEESRRK
